Table 3 Primary and secondary outcomes of the ‘Save the Kidney’-bundle
Outcome | Usual care group | STK group | RR (95%CI) P-value |
|---|---|---|---|
Number of patients | 1295 | 1347 | |
Primary outcome (AKI progression, need for RRT and ICU mortality) (N (%)) | 388 (30) | 465 (36) | 1.15 (1.03–1.29) |
0.001 (*) | |||
Overall ICU mortality (N (%)) | 72 (5.6) | 91 (6.8) | 1.22 (0.90–1.64) |
0.068 (*) | |||
Need for RRT during ICU admission (N (%)) | 46 (3.6) | 22 (1.6) | 0.46 (0.28–0.76) |
0.002 (*) | |||
AKI progression (N (%)) | 326 (25) | 402 (31) | 1.19 (1.05–1.34) |
0.001 (**) | |||
Maximum AKI stage during 48 h | 0.87 (0.82–0.93) | ||
No AKI (N (%)) | 863(67) | 783 (61) | < 0.001 (***) |
AKI stage 1 (N (%)) | 238 (18) | 299 (23) | 1.21 (1.04–1.41) |
AKI stage 2 (N (%)) | 128 (10) | 169 (13) | 1.27 (1.02–1.58) |
AKI stage 3 (N (%)) | 66 (5.1) | 41 (3.2) | 0.6 (0.41–0.88) |
ICU LoS (days; median [IQR]) | 2 [2–3] | 2 [2–3] | 0.319 (*) |
Hospital mortality (N (%)) | 117 (9) | 137 (10.2) | 0.248 (*) |