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Table 1 Participant summary characteristics comparisons for CKD stages 1–2 and CKD stages 3–5

From: Association of retinal venular tortuosity with impaired renal function in the Northern Ireland Cohort for the Longitudinal Study of Ageing

Participant characteristic scr

All (n = 1860)

CKD stages 1–2 (n = 1713)

CKD stages 3–5 (n = 147)

P Value

Mean age (years, SD)

62.0 ± 8.5

61.3 ± 8.1

70.5 ± 9.0

< 0.01

Female, n (%)

994 (53.4)

930 (54.3)

64 (43.5)

0.01

Education, primary level and below, n (%)

238 (12.8)

210 (12.6)

28 (19.0)

0.02

Diabetes, yes n (%)

429 (23.1)

380 (22.2)

49 (33.3)

< 0.01

Mean BMI (kg/m2, SD)

28.6 ± 5.0

28.5 ± 5.0

29.2 ± 4.4

0.12

Mean systolic blood pressure (mmHg, SD)

131.1 ± 18

131 ± 18

133 ± 19

0.27

Antihypertension medication, yes n (%)

506 (27.2)

438 (25.6)

68 (46.3)

< 0.01

Mean triglyceride (mmol/L, SD)

1.7 ± 1.0

1.6 ± 1.0

1.8 ± 0.8

0.11

Mean HDL cholesterol (mmol/L, SD)

1.6 ± 0.5

1.6 ± 0.4

1.5 ± 0.5

< 0.01

Mean LDL cholesterol (mmol/L, SD)

3.5 ± 1.1

3.5 ± 1.1

3.1 ± 1.2

< 0.01

Cardiovascular disease, yes n (%)

143 (7.7)

111 (6.5)

32 (21.8)

< 0.01

Mean eGFR Creatinine (mL/min/1.73m2, SD)

82.2 ± 14.9

85.0 ± 11.7

49.6 ± 7.8

< 0.01

Participant characteristic cys

All (n = 1860)

CKD stages 1–2 (n = 1362)

CKD stages 3–5 (n = 498)

P Value

Mean age (years, SD)

62.0 ± 8.5

59.8 ± 7.4

68.2 ± 8.3

< 0.01

Female, n (%)

994 (53.4)

739 (54.3)

255 (51.2)

0.24

Education, primary level and below, n (%)

238 (12.8)

138 (10.1)

100 (20.1)

< 0.01

Diabetes, yes n (%)

429 (23.1)

271 (19.9)

158 (31.7)

< 0.01

Mean BMI (kg/m2, SD)

28.6 ± 5.0

28.0 ± 4.5

30.3 ± 5.6

< 0.01

Mean systolic blood pressure (mmHg, SD)

131.1 ± 18

130 ± 19

133 ± 18

< 0.01

Antihypertension medication, yes n (%)

506 (27.2)

297 (21.8)

209 (42.0)

< 0.01

Mean triglyceride (mmol/L, SD)

1.7 ± 1.0

1.6 ± 0.9

1.8 ± 1.0

< 0.01

Mean HDL cholesterol (mmol/L, SD)

1.6 ± 0.5

1.7 ± 0.5

1.6 ± 0.4

< 0.01

Mean LDL cholesterol (mmol/L, SD)

3.5 ± 1.1

3.5 ± 1.1

3.2 ± 1.2

< 0.01

Cardiovascular disease, yes n (%)

143 (7.7)

73 (5.4)

70 (14.1)

< 0.01

Mean eGFR Cystatin C (mL/min/1.73m2, SD)

70.7 ± 18.6

78.6 ± 14.7

49.1 ± 8.0

< 0.01

  1. Values are n (%) for categorical variables and mean ± SD for continuous variables. P values were calculated by independent sample t and chi squared tests. Abbreviations: CKD Chronic Kidney Disease, BMI Body Mass Index, eGFR Estimated glomerular filtration rate (calculated using the CKD-EPI equation), HDL High-density Lipoprotein, LDL Low-density Lipoprotein, scr Serum Creatinine, cys Serum Cystatin C, SD Standard deviation