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Table 2 Associations between sociodemographic and anthropometric characteristics and eGFR/eGFR< 90 in participants without diabetes, hypertension, proteinuria, n = 821

From: Prevalence and risk factors for chronic kidney disease of unknown cause in Malawi: a cross-sectional analysis in a rural and urban population

Variable

Model 1 Minimal adjustment

Model 2 Fully adjusted

Model 3 Minimal adjustment

Model 4Fully adjusted

eGFR

eGFR

eGFR < 90

eGFR < 90

Coefficient (95%CI)a;

Coefficient (95%CI)b;

OR (95%CI)a;

OR (95%CI)b;

Age c (per 10-year increase)

−8.73 (−9.37, −8.09)

−8.86 (−9.60, −8.15)

3.21 (2.49, 4.29)

3.59 (2.58, 5.21)

Sex d

 Male

0.02 (−1.62, 1.68)

−0.45 (−2.40, 1.47)

0.76 (0.34, 1.67)

1.44 (0.48, 5.05)

 Female

Ref

Ref

Ref

Ref

Area

 Urban (Area 25)

Ref

Ref

Ref

Ref

 Rural (Bonje)

3.85 (2.05, 5.64)

3.82 (1.51, 6.32)

0.69 (0.27, 1.92)

1.75 (0.50, 6.30)

Education (years)

 ≤ 5

4.51 (1.10, 7.93)

4.29 (0.77, 7.69)

0.55 (0.14, 2.02)

0.64 (0.14, 2.56)

 > 5 ≤ 10

1.29 (−0.56, 3.15)

1.31 (− 0.57, 3.18)

0.78 (0.30, 2.03)

0.86 (0.31, 2.39)

 > 10

Ref

Ref

Ref

Ref

Occupation

 Agricultural worker

−1.06 (−3.14, 1.01)

− 1.11 (− 3.20, 1.02)

0.44 (0.17, 1.21)

0.42 (0.15, 1.17)

 Non-agricultural worker

Ref

Ref

Ref

Ref

Household monthly income (MK) e

 Unknown

−1.86 (−7.60, 3.87)

−2.26 (−8.01, 3.50)

1.39 (0.06, 13.66)

2.21 (0.09, 20.58)

 MK 0 ≤ 20,000

Ref

Ref

Ref

Ref

 MK > 20,000

−0.34 (−2.16, 1.47)

− 0.01 (− 1.85, 1.87)

1.32 (0.54, 3.23)

1.05 (0.40, 2.78)

BMI (kg/m2)

 5 kg/m2 increase

−0.99 (−2.8, 0.09)

− 0.94 (− 2.02, 0.17)

2.00 (1.29 3.15)

2.01 (1.27, 3.43)

Fat Free Mass (kg)

 (Per 5 kg increase)

−0.02 (− 0.07, 0.02)

−0.02 (− 0.07, 0.02)

1.00 (0.00, 1.02)

0.99 (0.03, 1.03)

Healthy lifestyle choices

 Non-smoker or alcohol drinker

−1.49 (−3.57, 0.59)

− 1.43 (− 3.50, 0.70)

2.07 (0.72, 6.64)

2.06 (0.68, 7.06)

 Smoker and alcohol drinker

Ref

Ref

Ref

Ref

Regular meat-eater

 Yes

−0.40 (−2.32, 1.51)

− 0.33 (− 2.27, 1.65)

1.34 (0.58, 3.39)

1.04 (0.43, 2.72)

 No

Ref

Ref

Ref

Ref

  1. Hypertension = systolic bp ≥140 mmHg, or diastolic bp ≥90 mmHg; Diabetes = fasting glucose > = 7 mg/l; Proteinuria = ACR > =30 mg/mmol
  2. aminimal adjustment for age, sex and area
  3. ball variables mutually adjusted
  4. cadjusted for sex and area
  5. dadjusted for age and area
  6. eExchange rate (MK to USD) 0.001 at time of questionnaire