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Table 4 Test parameters and results of diagnostics tests combining the two variables, urine neutrophil gelatinase-associated lipocalin at 6 h (uNGAL 6 h) and urine output 24 h before CRRT discontinuation (OUC24pre)

From: Urine neutrophil gelatinase-associated lipocalin and urine output as predictors of the successful discontinuation of continuous renal replacement therapy in critically ill patients with acute kidney injury

Test uNGAL> 1650 μg/L or urine output < 210 ml uNGAL> 1650 μg/L and urine output < 210 ml
  Non-recovery Recovery Non-recovery Recovery
Test positive 28 9 23 2
Test negative 1 13 6 20
Sensitivity 0.97 0.79
Specificity 0.59 0.91
NPV 0.93 0.77
PPV 0.76 0.92
  1. Each of the 2 tests are to be seen as a complete diagnostic test with 2 variables. E.g., for “uNGAL > 1650 um/L or urine output < 210 ml” the test is positive, if either or both “uNGAL > 1650” or “urine output < 210 ml” are true. The test is negative if neither of “uNGAL > 1650” or “urine output < 210 ml” are true. PPV = positive predictive value; NPV = negative predictive value
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