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Table 4 Test parameters and results of diagnostics tests combining the two variables, urine neutrophil gelatinase-associated lipocalin at 6 h (uNGAL 6 h) and urine output 24 h before CRRT discontinuation (OUC24pre)

From: Urine neutrophil gelatinase-associated lipocalin and urine output as predictors of the successful discontinuation of continuous renal replacement therapy in critically ill patients with acute kidney injury

Test

uNGAL> 1650 μg/L or urine output < 210 ml

uNGAL> 1650 μg/L and urine output < 210 ml

 

Non-recovery

Recovery

Non-recovery

Recovery

Test positive

28

9

23

2

Test negative

1

13

6

20

Sensitivity

0.97

0.79

Specificity

0.59

0.91

NPV

0.93

0.77

PPV

0.76

0.92

  1. Each of the 2 tests are to be seen as a complete diagnostic test with 2 variables. E.g., for “uNGAL > 1650 um/L or urine output < 210 ml” the test is positive, if either or both “uNGAL > 1650” or “urine output < 210 ml” are true. The test is negative if neither of “uNGAL > 1650” or “urine output < 210 ml” are true. PPV = positive predictive value; NPV = negative predictive value