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Table 1 Polymorphisms of the MYH9 gene associated with CKD traits. Data for variables with P < 0.05 are shown in bold

From: Effect of donor non-muscle myosin heavy chain (MYH9) gene polymorphisms on clinically relevant kidney allograft dysfunction

SNP risk variant European Americans non-diabetic [10] European Americans [16] Spanish Caucasians [11] European isolated cohorts [5]
Microsa Visb ERFc Meta-analysis of Micros, VIS, ERF
  eGFR< 60 ml/min FSGS eGFR< 60 ml/min serum creatinine increment (mg/dl)
OR (95% CI) p OR (95% CI) p OR (95% CI) p b# (SE) p b# (SE) p b# (SE) p b# (SE) p
rs3752462 T   2.42 (1.17–5.04) .01 1.99 (1.20–3.31) .007     
rs11089788 C     −0.0108 (0.0061) .0782 −0.0204 (0.0143) .1555 −0.0109 (0.0075) .1465 −0.0118 (0.0045) .0089
rs5756168 C     0.0284 (0.0097) .0034 −0.0436 (0.0255) .0875 0.0144 (0.0108) .1839 0.0173 (0.0069) .0127
rs2239784 T     0.0309 (0.0142) .0294 −0.0069 (0.0269) .7983 0.0158 (0.0172) .3560 −0.0112 (0.0101) .2674
rs136211 A     −0.0021 (0.0067) .7502 −0.0406 (0.0162) .0123 0.01240.0075) .1009 0.0004 (0.0048) .9414
rs4821480 G 1.44 (1.15–1.80) 0.001 9.73 (1.07–463) .02      
  1. table adapted from Liu L et at [16] supplemented with data from Pattaro et al. [12]
  2. #linear regression coefficients (b) and SE, assuming an additive genetic model adjusted for sex and age
  3. aMICROS cohort - The Genetic Study of three Population Microisolates in South Tyrol, Italy
  4. bVis cohort- CROATIA-Vis study
  5. cERF cohort, Erasmus Rucphen Family study, Netherlands