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Table 2 Light (LM) and electron microscopic (EM) findings in renal biopsies in 11 patients with HIV and membranous nephropathy

From: Membranous nephropathy in patients with HIV: a report of 11 cases

Patient

Diagnoses

Total glomeruli*

GS (%)

IFTA (%)

FSGS

Arteriosclerosis

EM Deposit location

EM MN stage

FPE (%)

1

MN

7

0

< 5

0

Normal/minimal

NA

NA

NA

2

HIVAN; MN; mild DN

42

43

90

Collapsing

Severe

Mes; SEpi (segmental); IM

II-III

60–70 (variable)

3

MN; TIN

38

5

10

0

Mild

SEpi; IM

II-IV

100

4

MN; TIN

39

3

 

0

Moderate

Mes; SEpi; IM

II-III

50 (variable)

5

MN

32

9

5

0

Mild

SEpi

I-II

100

6

MN

46

42

75

NOS

Severe

SEpi; IM

II-III

100

7

MN

25

12

10

0

Mild

SEpi

I-II

100

8

MN

28

0

5

0

Moderate

SEpi

II

100

9

MN

14

36

50

0

Moderate

SEpi

III

100

10

MN; LLN

28

0

10

0

Mild

Mes (rare); SEndo (rare); SEpi (segmental)

I

60–70 (variable)

11

MN

45

13

30

NOS

Severe

Mes; SEpi

IV

80%

  1. Abbreviations: GS: glomerulosclerosis; IFTA: interstitial fibrosis and tubular atrophy; FSGS: focal and segmental glomerulosclerosis; FPE: foot process effacement; MN: membranous nephropathy; TIN: tubulointerstitial nephritis; LLN: lupus-like nephropathy; DN: diabetic nephropathy; Mes.: mesangial; SEpi.: subepithelial (diffuse unless otherwise specified); SEndo.: subendothelial; IM: intramembranous. Deposits are considered diffuse unless otherwise specified. *Describes total glomeruli sampled for LM, EM, and IF