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Table 2 Urinalysis and autoimmune screen results

From: Histological diagnosis of immune checkpoint inhibitor induced acute renal injury in patients with metastatic melanoma: a retrospective case series report

Patient Baseline Urinalysis Urinalysis at AKI Autoimmune screen
Haematuria Pyuria Proteinuria Culture / Casts Haematuria Pyuria Proteinuria Culture / Casts
1 - - - - - - - - negative
2 NA NA NA NA - - - - negative
3 - + - - - - - - negative
4 NA NA NA NA - + - - negative
5 - + - - - + + - Not available
6 NA NA NA NA - + + - Not available
7 - - - - - + + Hyaline casts ANA 1:2560.
8 NA NA NA NA + + - E. cloacae UTI Not available
9 - - - - - - NA - negative
10 NA NA NA NA + + N/A E. Coli infection anti GBM 614u/mL
11 - - - - - - + - ANA 1:80
12 NA NA NA NA + + + - negative
13 - - - - - - + - negative
14 + - - - - + - - negative
15 - - - NA + + + - negative
16 + Nil + - + + + Hyaline casts ANA 1:40
17 - - - NA + + - - Not available
18 - - - - - - - - negative
19 - - - - - - - - negative
20 + + NA - + + + - Negative
21 NA NA NA NA + + - - pANCA+ve MPO/PR3 negative
22 + + - - - + - - negative
23 - - + NA - - + - ANA 1:80
  1. NA – not available. Haematuria – > 10 red cells per high power field on microscopy or > 1+ on urine dipstick. Pyuria – > 10 white cells per high power field on microscopy or > 1+ on urine dip stick. Proteinuria – raised albumin/protein:creatinine ratio or > 1+ protein on urine dip stick. ANA – Anti Nuclear Antibody; ANCA – Anti Neutrophil Cytoplasmic Antibody; antiGBM – Glomerular Basement Membrane; MPO – Myeloperoxidase; PR3 – Proteinase 3
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