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Table 1 Patient characteristics

From: Independent risk factors and long-term outcomes for acute kidney injury in pediatric patients undergoing hematopoietic stem cell transplantation: a retrospective cohort study

  Whole cohort(n = 43) AKI(n = 21) Non-AKI(n = 22) P-value
Age at HSCT, years, median (IQR) 5.5 (4.1–10.8) 5.5 (4.2–14.4) 5.2 (4.1–7.8) 0.37
Sex, Male, n (%) 28 (65) 14 (67) 14 (64) 0.84
Indication for HSCT
 Malignant 34 (79) 18 (86) 16 (73) 0.46
Conditioning regimen, n (%)
 Calcineurin inhibitor 4 (9) 2 (10) 2 (9) 1.00
 TBI use 22 (51) 15 (71) 7 (32) < 0.01
Stem cell source, n (%)
 Bone marrow 19 (44) 9 (43) 10 (45) 0.86
 Peripheral blood 21 (49) 9 (43) 12 (55) 0.44
 Umbilical cord 3 (7) 3 (14) 0 (0) 0.11
Donor source, n (%)
 Autologous 20 (46) 7 (33) 13 (59) 0.091
 MRD 5 (12) 1 (5) 4 (18) 0.35
 MUD 18 (42) 13 (62) 5 (23) < 0.01
Acute GVHD, n (%) 20 (47) 12 (67) 8 (36) 0.17
I 8 (19) 4 (18) 4 (18) 1.00
II – IV 12 (28) 8 (38) 4 (19) 0.19
  1. HSCT, hematopoietic stem cell transplantation; TBI, total body irradiation; MRD, matched related donor; MUD, matched unrelated donor; GVHD, graft-versus-host disease