Table 1 Socio-demographic, haematological and biochemical characteristics of participants by iron-deficiency-anaemia status
Characteristics | CKD (n = 312) | Controls (n = 184) | ||||
|---|---|---|---|---|---|---|
|  | IDA n = 103 (%) | Non-anaemic n = 209 (%) | P-value | IDA n = 18 (%) | Non-anaemic n = 166 (%) | P-value |
Hepcidin (ng/ml) (median, IQR) | 8.4 (4–45.5) | 6.8 (3.9–33.6) | 0.2790 | 3.1 (2.3–7.9) | 3.1 (2.1–10.9) | 0.836 |
GDF-15 (pg/ml) (median, IQR) | 1256.8 (919.1–1618) | 700 (335.1–1327.8) | < 0.0001 | 1175.9 (708.9–1267.1) | 397.95 (183.2–1101) | 0.016 |
Age (mean ± SD) years | 54.5 ± 15.2 | 54.3 ± 14.2 | 0.9340 | 45.2 ± 17.5 | 41.3 ± 13.6 | 0.255 |
< 40 | 15 (14.6) | 37 (17.7) | 0.484 | 8 (44.4) | 79 (47.6) | 0.800 |
≥40 | 88 (82.3) | 172 (85.4) |  | 10 (55.6) | 87 (52.4) |  |
Race | ||||||
Blacks | 95 (92.2) | 165 (79.0) | 0.003 | 12 (66.7) | 133 (80.1) | 0.185 |
Whites | 8 (7.8) | 44 (21.1) | Â | 6 (33.3) | 33 (19.9) | Â |
Gender | ||||||
Male | 41 (39.8) | 126 (60.3) | 0.001 | 7 (38.9) | 71 (42.8) | 0.752 |
Female | 62 (60.2) | 83 (39.7) | Â | 11 (61.1) | 95 (57.2) | Â |
Systolic Blood Pressure (median, IQR) (mmHg) | 139 (125–157) | 140 (130–160) | 0.1994 | 132 (120–140) | 132 (130–140) | 0.998 |
Diastolic Blood Pressure (median, IQR) (mmHg) | 80 (70–91) | 80 (70–90) | 0.6234 | 81 (70–90) | 80 (72–90) | 0.7707 |
Serum Urea (median, IQR) (mmol/L) | 17.1 (9.8–25.7) | 11 (7.1–15.9) | 0.0001 | 4 (3–4.9) | 4.35 (3.6–5.2) | 0.4486 |
Serum Creatinine (median, IQR), μmol/L | 265 (158–520) | 171 (120–255) | < 0.0001 | 70.5 (64–78) | 78.5 69–91) | < 0.0001 |
eGFR (median, IQR), mls/min/1.73m2 | 27.0 (12.6–27.0) | 43.6 (27.7–66.0 | < 0.0001 | 129.8 (96.3–139.5) | 114.4 (96.8–133.0) | 0.3490 |