From: Lower serum sodium levels predict poor clinical outcomes in patients with insomnia
Variables | Total (N = 412) | <  138.0 mg/dL (N = 147) | 138.0–140.9 mg/dL (N = 136) | ≥141.0 mg/dL (N = 129) | P |
---|---|---|---|---|---|
Age (yr) | 61.5 ± 14.8 | 63.4 ± 14.2 | 60.4 ± 16.1 | 60.4 ± 13.8 | 0.150 |
Men (%) | 231 (56.1) | 93 (63.3) | 77 (56.6) | 61 (47.3) | 0.028 |
Body mass index (kg/m2) | 23.5 ± 2.2 | 23.3 ± 2.0 | 23.6 ± 2.3 | 23.6 ± 2.2 | 0.431 |
Systolic blood pressure (mmHg) | 124.2 ± 12.1 | 123.8 ± 11.9 | 124.7 ± 12.1 | 124.1 ± 12.5 | 0.826 |
Diastolic blood pressure (mmHg) | 79.8 ± 7.8 | 79.9. ± 7.3 | 80.0 ± 8.0 | 79.5 ± 8.1 | 0.906 |
Serum sodium, (mmol/L) | 138.9 ± 3.7 | 135.0 ± 2.9 | 139.6 ± 0.9 | 142.5 ± 1.6 | <  0.001 |
Serum potassium (mmol/L) | 4.1 ± 0.5 | 4.2 ± 0.5 | 4.2 ± 0.5 | 4.1 ± 0.5 | 0.570 |
Hemoglobin (g/dL) | 12.6 ± 2.0 | 12.2 ± 1.9 | 12.8 ± 2.0 | 12.7 ± 2.0 | 0.012 |
Calcium (mg/dL) | 8.9 ± 0.7 | 8.7 ± 0.6 | 9.0 ± 0.6 | 9.0 ± 0.6 | <  0.001 |
Phosphorus (mg/dL) | 3.5 ± 0.8 | 3.4 ± 0.9 | 3.6 ± 0.7 | 3.7 ± 0.7 | 0.025 |
Glucose (mg/dL) | 129.9 ± 50.2 | 137.7 ± 59.6 | 130.9 ± 46.4 | 120.1 ± 40.1 | 0.015 |
Total Protein (g/dL) | 6.5 ± 0.8 | 6.3 ± 0.8 | 6.6 ± 0.8 | 6.5 ± 0.7 | 0.043 |
Albumin (g/dL) | 3.8 ± 0.7 | 3.5 ± 0.7 | 4.0 ± 0.7 | 4.0 ± 0.6 | <  0.001 |
Cholesterol (mg/dL) | 165.9 ± 45.2 | 159.6 ± 52.6 | 170.9 ± 41.7 | 171.5 ± 37.4 | 0.007 |
Uric acid (mg/dL) | 4.6 ± 1.7 | 4.0 ± 1.9 | 4.8 ± 1.5 | 5.0 ± 1.6 | <  0.001 |
eGFR (mL/min/1.73m2) | 88.3 ± 24.8 | 89.0 ± 28.1 | 88.4 ± 22.4 | 87.4 ± 22.4 | 0.787 |
Follow up duration (month) | 49.4 ± 29.0 | 42.5 ± 29.2 | 53.8 ± 27.7 | 52.9 ± 28.9 | 0.001 |
Charlson Comorbidity Index (CCI) Score |  |  |  |  | < 0.001 |
CCI score 0–2 (%) | 161 (39.1) | 36 (24.5) | 61 (44.9) | 64 (49.6) |  |
CCI score 3–4 (%) | 145 (35.2) | 56 (38.1) | 47 (34.6) | 42 (32.6) |  |
CCI score ≥ 5 (%) | 106 (25.7) | 55 (37.4) | 28 (20.6) | 23 (17.8) |  |
Use of thiazide (%) | 32 (7.8) | 12 (8.2) | 11 (8.1) | 9 (7.0) | 0.920 |