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Table 3 Comparison of genotype frequencies for rs1494558 and rs2232365 and their risks of NODAT in Malaysian renal transplant recipients presented as HR and 95% CI

From: Clinical and genetic risk factors for new-onset diabetes mellitus after transplantation (NODAT) in major transplant centres in Malaysia

Genotype NODAT (n, %) Non NODAT (n, %) Unadjusted
HR (95% CI), p
Adjusteda
HR (95% CI), p
rs1494558
 - AA (n = 43) 6 (14%) 37 (86%) ref ref
 - GA (n = 97) 18 (19%) 79 (81%) 1.98 (1.09, 3.61), 0.02 3.15 (1.26, 7.86), 0.01
 - GG (n = 27) 4 (15%) 23 (85%) 1.44 (0.66, 3.15), 0.36 1.22 (0.31, 4.91), 0.77
rs2232365
 - AA (n = 79) 12 (15%) 67 (85%) ref ref
 - AG (n = 31) 5 (16%) 26 (84%) 0.86 (0.47, 1.57), 0.62 2.57 (1.07, 6.18), 0.04
 - GG (n = 57) 11 (11%) 46 (81%) 0.98 (0.61, 1.58), 0.95 0.80 (0.39, 1.66), 0.55
  1. aAdjusted for ethnicities, age at transplant, primary kidney disease, duration of dialysis pre-transplant and average daily doses of immunosuppressants