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Table 3 Concentration of platelet-derived growth factors of patients with chronic renal disease hemodialysed (before and after HD A, HD B), peritoneal dialysis (PD), conservative treatment (CT), before and after kidney transplantation (TE, TE A) and in the control group (NK) (mean ± OS, median – lower and upper quartile)

From: Effect of renal replacement therapy on selected arachidonic acid derivatives concentration

Concentration of arachidonic acid derivatives

Groups

TXB2 [ng/mL]

5-HETE [ng/mL]

12-HETE [ng/mL]

15-HETE [ng/mL]

HD A

34,6 ± 9

284,2 ± 428,4

3,0 ± 0,4

18,1 ± 8,7

36,9 (29,8; 41,8)

76,8 (1,34; 1465)

2,83 (2,5; 4)

17,0 (4,4; 40,1)

HD B

34,3 ± 10,5

304,8 ± 516,2

3,1 ± 0,6

42,2 ± 14,8

38,5 (30,7; 40,9)

65,92 (1,11; 1580)

3,0 (1,3; 4,9)

44,9 (18,3; 76,1)

PD

28,3 ± 15,2

530,0 ± 553,3

3,1 ± 2,1

36,3 ± 13,8

29,8 (17,8; 37,4)

199,4 (11,6; 1511)

3,0 (0,1; 13,2)

38,5 (11,6; 68,6)

CT

34,2 ± 8,0

318,7 ± 366,0

3,0 ± 0,8

33,7 ± 14,0

35,6 (26,9; 42,3)

151,4 (8,4; 1333,3)

3,2 (0,1; 4,1)

28,8 (13,4; 65,9)

TE

36,7 ± 42,9

525,6 ± 358,0

3,7 ± 1,9

19,5 ± 10,2

23,16 (14,18; 38,7)

622,6 (25,7; 1219,0)

2,8 (1,8; 8,8)

15,8 (1,9; 43,6)

TE A

27,9 ± 8,8

409,8 ± 377,1

2,8 ± 0,8

34,4 ± 16,3

26,7 (20,9; 34,7)

265,4 (13,6; 1157)

2,7 (0,1; 4,8)

35,4 (7,2; 73,0)

NK

19,6 ± 15

838,1 ± 497,8

3,3 ± 1,0

22,2 ± 17,8

18,3 (10,0; 25,5)

792,0 (21,9; 1933,8)

3,1 (1,5; 6,9)

19,4 (0,2; 89,2)

P

0,010

< 0,001

NS

< 0,001