| |
Total
|
Acute kidney injury
|
Neurologic outcome at discharge
|
|---|
|
(−)
|
(+)
|
p-value
|
Good
|
Poor
|
p-value
|
|---|
|
NGAL at ROSC
|
124.0
|
(96.0–186.0)
|
105.5
|
(83.3–143.3)
|
142.0
|
(107.0–263.0)
|
0.001
|
105.0
|
(84.0–141.0)
|
140.0
|
(140.6–245.8)
|
0.002
|
|
NGAL at 3 h after ROSC
|
181.0
|
(115.0–381.0)
|
115.0
|
(84.3–145.5)
|
353.0
|
(223.0–510.0)
|
< 0.001
|
134.0
|
(84.0–181.0)
|
255.5
|
(139.5–434.8)
|
< 0.001
|
|
CRRT
|
11
|
(14.7)
|
0
|
(0.0)
|
11
|
(23.4)
|
0.005
|
1
|
(3.6)
|
10
|
(23.1)
|
0.045
|
|
CAG
|
40
|
(44.9)
|
25
|
(62.5)
|
15
|
(30.6)
|
0.003
|
30
|
(85.7)
|
10
|
(18.5)
|
< 0.001
|
|
Target temperature
| | | | | | |
0.586
| | | | |
0.559
|
|
33 °C
|
86
|
(96.6)
|
38
|
(95.0)
|
48
|
(98.0)
| |
33
|
(94.3)
|
53
|
(98.1)
| |
|
< 36 °C
|
3
|
(3.4)
|
2
|
(5.0)
|
1
|
(2.0)
| |
2
|
(5.7)
|
1
|
(1.9)
| |
|
TTM duration
| | | | | | |
0.624
| | | | |
1.000
|
|
24 h
|
85
|
(95.5)
|
39
|
(97.5)
|
46
|
(93.9)
| |
34
|
(97.1)
|
51
|
(94.4)
| |
|
48 h
|
4
|
(4.5)
|
1
|
(2.5)
|
3
|
(6.1)
| |
1
|
(2.9)
|
3
|
(5.6)
| |
|
Survival discharge
|
48
|
(53.9)
|
34
|
(85.0)
|
14
|
(28.6)
|
< 0.001
|
35
|
(100.0)
|
13
|
(24.1)
|
< 0.001
|
|
CPC at discharge
| | | | | | |
< 0.001
| | | | | |
|
Good (1,2)
|
35
|
(39.3)
|
26
|
(65.0)
|
9
|
(18.4)
| | | | | | |
|
Poor (3,4,5)
|
54
|
(60.7)
|
14
|
(35.0)
|
40
|
(81.6)
| | | | | | |
|
Survival at 1 month
|
47
|
(52.8)
|
33
|
(82.5)
|
14
|
(28.6)
|
< 0.001
|
35
|
(100.0)
|
12
|
(22.2)
|
< 0.001
|
|
Survival at 6 months
|
47
|
(53.4)
|
33
|
(82.5)
|
14
|
(29.2)
|
< 0.001
|
35
|
(100.0)
|
12
|
(22.6)
|
< 0.001
|
- Quantitative data are expressed as median (interquartile range), categorical data are presented as number of subjects (percentages). Mann-Whitney U test was used for continuous variable analysis, while chi-squared test or Fisher’s exact test were used for categorical variable analysis as appropriate
- NGAL neutrophil gelatinase-associated lipocalin, ROSC return of spontaneous circulation, CRRT continuous renal replacement therapy, CAG coronary angiography, TTM targeted temperature management, CPC cerebral performance category
