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Table 2 Histopathology characteristics on renal biopsy

From: C3-glomerulonephritis in New Zealand – a case series

Biopsy characteristic

All patients (n = 26, (%)

Pattern on light microscopy

 Membranoproliferative

18 (69)

 Diffuse proliferative

5 (19)

 Crescentic

2 (8)

 Mesangial proliferative

1 (4)

Immunofluorescent staining other than C3

 IgM

9 (35)

 IgG

6 (23)

 IgA

2 (8)

 C1q

1 (4)

 Kappa / lambda

0 (0)

Presence of EM deposits, no. (%)

 Subepithelial

17 (65)

 Subendothelial

16 (62)

 Mesangial

22 (85)

 Intramembranous

9 (35)

Interstitial infiltrate, no. (%)

17 (65)

Intimal fibrosis, no. (%)

7 (27)

Scarring, median % (IQR)

7.5 (0–25)

Crescents, no. (%)

5 (19)

  1. *EM Electron microscopy