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Table 4 Treatment and outcome of seven patients with mixed cryoglobulinemic glomerulonephritis associated with HBV infection

From: Clinicopathological study of mixed cryoglobulinemic glomerulonephritis secondary to hepatitis B virus infection

Case Anti-viral Immunosuppressive therapy Follow-up time (months) Scr (μmol/L) eGFR (ml/min per 1.73m2) 24hUP (g/d) Cryocrit(%) HBV-DNA (copies/ml) Outcome
1 ETV CS + MMF 37 90 67.00 0.80 NA < 103 PR
2 ETV CS + CYC + DFPP 22 99 55.30 2.05 7.0 < 103 PR
3 ETV CS + CYC + DFPP 6 60 111.80 0.05 0 < 103 CR
4 LAM CS + CYC 3 119 54.13 3.77 NA NA death
5 ETV CS 62 80 114.00 0.90 2.0 1.24 × 104 PR
6 ETV CS 12 287 20.70 5.22 NA NA death
7 ETV CS + CYC 18 900 5.50 9.92 0 < 103 dialysis
  1. Scr Serum creatinine, eGFR Estimated glomerular filtration rate, 24hUP 24-h urine protein, ETV Entecavir, LAM Lamivudine, CS Corticosteroid, MMF Mycophenolate, CYC Cyclophosphamide, DFPP Double-filtration plasmapheresis, CR Complete remission, PR Partial remission, NA Not available