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Table 1 Baseline patient characteristics and differences between the MCD group and non-MCD group

From: Establishment of a novel nomogram for the clinically diagnostic prediction of minimal change disease, −a common cause of nephrotic syndrome

Characteristics
[median (Q1, Q3)]
TOTAL
(n = 1009)
MCD
(n = 71)
Non-MCD
(n = 938)
Z P value
Age (years) 41 (28,53) 36 (22,55) 41 (28.75,53) − 1.193 0.2
Sex (male/female), n 532/477 42/29 490/448 / /
SBP (mmHg) 124 (114,137) 121 (109,132) 125 (114,138) −2.097 0.04 *
DBP (mmHg) 80 (73,89) 79 (71,85.5) 80 (74,89) −2.223 0.03 *
Height (cm) 165 (160,172) 166 (163,172) 165 (160,172) −0.891 0.4
Weight (kg) 65 (56,75) 63.25 (55.25,75.5) 65 (56,75) −0.604 0.5
BMI (kg/m2) 23.705 (20.960,26.515) 23.63 (20.52,27.05) 23.73 (21,26.4) −0.263 0.8
Glu (mmol/L) 4.81 (4.39,5.39) 4.625 (4.19,5.075) 4.83 (4.41,5.4) −1.898 0.06
WBC (*109 /L) 6.37 (5.18,7.89) 6.52 (4.84,7.98) 6.36 (5.19,7.89) −0.227 0.8
HB (g/L) 133 (116,147) 142 (133,155) 132 (115,146) −4.578 <0.001 *
PLT (*109 /L) 224 (179,269) 253.5 (212.5293.25) 221 (177.5266) −3.628 <0.001 *
RBC (*1012 /L) 4.4 (3.91,4.84) 4.66 (4.33,5.09) 4.37 (3.88,4.81) −3.975 <0.001*
NE (%) 63 (55.9,69.8) 62.34 (55.1,69.1) 63.05 (56,69.875) −0.432 0.7
EO (%) 1.5 (0.655,2.8) 1.4 (0.4,2.8) 1.5 (0.7,2.8) −0.804 0.4
LY (%) 27.8 (20.65,33.8) 28.02 (21.575,34.7) 27.64 (20.5,33.7) −0.982 0.3
MO (%) 5.7 (4.5,7.3) 5.75 (4.7,7.875) 5.7 (4.5,7.2) −0.959 0.3
IgG (g/L) 9.09 (6.2175,11.8) 5.415 (3.1725,6.3575) 9.375 (6.79,12.0225) −8.922 <0.001 *
IgA (g/L) 2.51 (1.87,3.32) 2.185 (1.735,2.945) 2.54 (1.88,3.34) −2.276 0.02 *
IgM (g/L) 1.06 (0.72,1.48) 1.44 (0.9632,1.88) 1.03 (0.7068,1.45) −4.187 <0.001 *
C3 (g/L) 1.07 (0.907,1.24) 1.19 (1.0575,1.425) 1.06 (0.897,1.23) −4.443 <0.001 *
C4 (g/L) 0.243 (0.1942,0.31) 0.272 (0.2253,0.3403) 0.24 (0.19,0.309) −3.136 0.002 *
IgE (IU/ml) 52.2 (19.4142) 160 (46.7982) 47.3 (19,126) −5.890 <0.001 *
C1q (g/L) 0.308 (0.266,0369) 0.369 (0.305,0.4205) 0.304 (0.263,0.3622) −5.092 <0.001 *
Urine protein
(mg/24 h)
2425 (1008.95004.2) 5284.62 (3786.54,9330.5) 2179.46 (973.4425,4599) −7.4 < 0.001*
eGFR (ml/min) 101.065 (66.68,124.035) 115.59 (82.23,135) 100.17 (65.07,123.48) −2.458 0.014*
Immunosuppressive therapy
 YES   66 548   
 NO   5 388   
 Missing data    2   
  1. *P < 0.05 MCD group vs. non-MCD group
  2. Abbreviations: SBP Systolic blood pressure, DBP Diastolic blood pressure, BMI Body mass index, Glu Glucose, WBC White blood count, HB Hemoglobin, PLT Platelet, RBC Red blood cell count, NE Neutrophil percentage, EO Eosinophil percentage, LY Lymphocyte percentage, MO Monocyte percentage, IgG Immunoglobulin G, IgA Immunoglobulin A, IgM Immunoglobulin M, C3 Complement 3, C4 Complement 4, IgE Immunoglobulin E, C1q Complement 1q
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