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Table 1 Clinical data and treatment at the time of renal biopsy

From: Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases

 

Diagnosis

Clinical data

Treatment

Gender

Blood pressure (mmHg)

sCr (mg/dL)

eGFR (mL/min/1.73m2)

Alb (g/dl)

Tchol (mg/dl)

HbA1c (%)

UPCR (g/gCr)

Duration of DM (years)

RAS inhibitor

DPP-4 inhibitor

Biguanide

SGLT2 inhibitor

SU

Glinide

αGI

Insulin

case 1

Minor glomerular abnormalitya

female

90/52

0.55

102.0

4.2

210

5.3

0.0

0

0

0

0

0

0

0

0

0

case 2

Minor glomerular abnormality

female

100/63

0.50

115.3

4.6

170

5.4

0.5

0

0

0

0

0

0

0

0

0

case 3

Minor glomerular abnormality

female

110/64

0.85

62.8

4.3

156

6.0

0.1

0

0

0

0

0

0

0

0

0

case 4

ANCA-RNa

female

122/64

2.37

17.6

3.1

258

6.0

2.7

0

0

0

0

0

0

0

0

0

case 5

ANCA-RN

female

110/60

2.08

20.6

3.7

199

5.6

0.6

0

1

0

0

0

0

0

0

0

case 6

ANCA-RN with DPP-4i

male

125/60

1.77

32.8

3.4

170

6.6

1.7

15

1

1

1

0

1

0

0

0

case 7

ANCA-RN

female

160/70

0.98

42.8

3.8

210

6.7

0.4

2

1

0

0

0

0

0

0

0

case 8

FSGSa

female

120/82

1.04

50.7

3.0

224

5.2

1.6

0

1

0

0

0

0

0

0

0

case 9

FSGS

male

120/78

1.02

60.1

2.0

369

5.1

6.7

0

0

0

0

0

0

0

0

0

case 10

FSGS

male

142/70

0.91

72.1

1.9

379

5.7

5.3

0

0

0

0

0

0

0

0

0

case 11

FSGS

male

122/72

0.92

76.0

4.0

170

5.1

0.4

0

0

0

0

0

0

0

0

0

case 12

FSGS

male

128/74

1.94

33.6

4.7

199

5.5

0.1

0

0

0

0

0

0

0

0

0

case 13

FSGS

female

122/62

1.03

48.3

4.0

217

5.3

2.8

0

1

0

0

0

0

0

0

0

case 14

FSGS

female

116/60

0.81

69.2

2.9

216

5.9

7.3

0

0

0

0

0

0

0

0

0

case 15

Nephrosclerosisa

male

122/78

0.75

76.3

4.1

218

5.9

0.0

0

1

0

0

0

0

0

0

0

case 16

DN w/o DPP-4iab

male

118/62

0.85

65.7

4.4

210

6.7

0.9

unknown

1

0

0

0

0

0

0

0

case 17

DN w/o DPP-4ib

male

132/78

1.50

48.4

3.4

208

6.4

5.0

20

1

0

0

1

0

0

0

1

case 18

DN w/o DPP-4ib

male

134/84

0.77

71.2

2.1

227

8.1

5.5

13

1

0

0

0

0

0

0

1

case 19

DN w/o DPP-4ib

female

140/80

0.36

137.1

2.6

267

12.7

3.2

unknown

0

1

1

0

0

0

0

0

case 20

DN with DPP-4i

male

162/66

2.21

24.2

2.4

274

7.1

4.5

27

1

1

0

0

1

1

1

0

case 21

DN with DPP-4i

male

138/76

2.00

32.7

2.4

245

9.3

6.3

4

0

1

0

0

0

0

0

0

case 22

DN with DPP-4i

male

130/70

2.00

29.2

3.9

150

6.4

7.3

3

1

1

0

0

0

0

0

0

case 23

DN with DPP-4i

male

138/68

1.82

29.3

4.4

162

6.0

0.7

30

1

1

1

0

1

0

0

0

case 24

DN with DPP-4i

male

152/78

0.76

74.8

3.9

184

7.0

0.2

10

1

1

0

1

1

0

0

0

case 25

DN with DPP-4ib

male

132/68

2.07

27.9

3.7

127

6.8

3.3

5

0

1

1

0

1

0

0

0

case 26

DN with DPP-4ib

male

112/82

0.58

106.0

4.1

564

8.1

2.8

6

1

1

1

1

0

0

0

1

case 27

DN with DPP-4ib

male

148/64

1.46

32.9

2.3

478

8.5

13.5

12

0

1

0

0

0

0

0

0

  1. ANCA-RN ANCA-related nephritis, FSGS focal segmental glomerular sclerosis, DN w/o DPP-4i diabetic nephropathy without DPP-4 inhibitor treatment, DN with DPP-4i diabetic nephropathy treated with DPP-4 inhibitor, sCr serum creatinine, eGFR estimemated glomerular filtration rate, Alb serum albumin, Tchol serum total cholesterol, UPCR urinary protein excretion, DM diabetes mellitus, RAS inhibitor renin−angiotensin system inhibitor, SU sulfonylurea, αGI α-glucosidase inhibitor, SGLT2 sodium glucose cotransporter 2
  2. 0: without treatment, 1:with treatment
  3. a: indicated in Fig. 1, b: indicated in Fig. 2