Table 2 Comparison of clinical features of HIV patients with and without anti-GBM antibodies
Parameters | with anti-GBM antibodies (n = 5) | without anti-GBM antibodies (n = 88) | P value |
|---|---|---|---|
Age (years) | 36.6 ± 9.8 | 36.3 ± 11.0 | 0.939 |
Gender (male/female) | 4/1 | 69/19 | 0.933 |
Stage (Asymptomatic/AIDS) | 4/1 | 44/44 | 0.192 |
CD4+T cell count (/μL) | 520.6 ± 171.6 | 146.8 ± 214.0 | 0.308 |
CD4/CD8 ratio | 0.77 ± 0.62 | 0.07 ± 0.05 | 0.235 |
HIV Load (Detected/NOT) | 1/4 | 29/59 | 0.052 |
Antiviral drug (Lamivudine/ Tenofovir fumarate/ Eferene) | 5/4/5 | 64/53/46 | 0.873 |
Hemoglobin (g/L) | 141.0 ± 32.1 | 125.8 ± 30.7 | 0.284 |
Serum urea (mmol/L) | 5.3 ± 0.6 | 4.2 ± 1.2 | 0.027* |
Serum creatinine (μmol/L) | 78.5 ± 25.1 | 59.8 ± 15.7 | 0.014* |
eGFR (ml/min/1.73m2) | 103.2 ± 24.1 | 121.8 ± 19.8 | 0.046* |
Infections (n, %) | 3, 60% | 17, 19.3% | 0.031* |
Positive urinary protein (n, %) | 0 | 16, 18.2% | 0.295 |