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Table 3 Characteristics of patients shifted toward to high category in Ca level during the 3-month intervals

From: Changes in 3-month mineral and bone disorder patterns were associated with all-cause mortality in prevalent hemodialysis patients with secondary hyperparathyroidism

 

M-L and M-M groups

M-H group

SMD

Demographics

 Age, years

62.0 ± 20.2

60.8 ± 19.6

0.06

 Sex, female, %

36.5

40.4

0.15

 Body mass index, kg/m2

21.5 ± 5.7

21.4 ± 5.6

0.01

 Cause of end-stage kidney disease, %

   

  Glomerulonephritis

39.3

46.6

 

  Diabetic nephropathy

29.4

22.6

0.17

  Others

31.4

30.8

 

Comorbidities, %

 Diabetes mellitus

36.9

28.5

0.18

 Cardiovascular diseases

58.6

57.8

0.02

 Lung diseases

7.2

7.0

0.01

 Liver diseases

12.8

13.8

0.03

 Malignancies

4.7

4.1

0.03

Dialysis

 Log duration of dialysis, years

0.7 ± 0.7

0.7 ± 12.6

0.14

 Kt/V, single pool

1.4 ± 0.5

1.5 ± 0.5

0.07

 Dialysate calcium, mEq/L

2.7 ± 0.4

2.8 ± 0.4

0.03

Laboratory data

 Albumin, g/dL

3.7 ± 0.5

3.7 ± 0.5

0.00

 Hemoglobin, g/dL

10.5 ± 1.8

10.6 ± 1.8

0.05

MBD-related characteristics

 Serum parameters

  P, mg/dL

5.4 ± 2.2

5.6 ± 2.2

0.09

  Log iPTH, pg/mL

2.3 ± 0.5

2.3 ± 0.5

0.05

 History of parathyroidectomy, %

4.4

6.2

0.08

 Prescription of MBD-related agents, %

  VDRAs

79.8

86.4

0.22

   Intravenous

45.3

55.4

 

   Oral

34.5

31.0

 

  Phosphate binders

85.8

89.5

0.16

   Both

26.4

31.4

 

   Non–Ca-based

15.0

17.3

 

   Ca-based

44.4

40.7

 

  Cinacalcet

19.3

28.2

0.21

  1. Values are presented as mean ± standard deviation for continuous variables and proportions for categorical variables
  2. Ca Calcium, H High, iPTH Intact parathyroid hormone, L Low, M Middle, MBD Mineral and bone disorder, P Phosphorus, SMD Standard mean difference, VDRA Vitamin D receptor activator