Table 1 Peritoneal concentrations of Amphotericin B [20,21,22,23,24]
Author and Year | Number in study | Antifungal Agent | Serum concentration (mg/L) | Peritoneal concentration (mg/L) | Peritoneal/serum penetration ratio |
|---|---|---|---|---|---|
Polak 1979 [21] | NR | Amphotericin B | 0.4 – 1.7 | 0.22 – 0.32 | 19–55% |
Petersen 1978 [22] | 1 | Amphotericin B | 0.52 (predose) 1.5 (postdose) | 0.44 (predose) 0.78 (postdose) | 85% 52% |
Van der Voort 2007 [23] | 21 | Amphotericin B | 0.25 (median) | 0.12 (median) | 41% |
Weiler 2008 [20] | 1 | Liposomal amphotericin | NR | 0.258 | NR |