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Table 1 Patient characteristics

From: High-sensitivity Troponin T in hemodialysis patients: a randomized placebo-controlled sub-study investigating angiotensin-II-blockade, variation over time and associations with clinical outcome

  

Placebo

ARB

  

(n = 40)

(n = 41)

Demographics

 Age

years

62 ± 14

61 ± 16

 Gender (males)

n (%)

25 (63)

30 (73)

 Body weight

kg

81 ± 17

79 ± 17

 Body mass index

kg/m2

27 ± 5

26 ± 5

 Diabetes

n (%)

12 (30)

13 (32)

 Heart disease

n (%)

17 (43)

15 (37)

 Ischemic heart disease

n (%)

9 (23)

8 (20)

 Charlson co-morbidity index

 

3.5 ± 1.6

3.8 ± 1.9

 LV mass index

g/m2

126 ± 36

126 ± 33

 LV EF

%

60 ± 9

62 ± 9

Cardiac medications

 Aspirin treatment

n (%)

21 (51)

16 (39)

 Antiplatelet (non-aspirin) drugs

n (%)

3 (7)

3 (7)

 Statin treatment

n (%)

21 (51)

15 (37)

 Nitrate medication

n (%)

6 (14)

4 (10)

BP and BP-medication

 Baseline systolic BP (preHD)

mmHg

145 ± 19

148 ± 21

 Baseline diastolic BP (preHD)

mmHg

72 ± 12

76 ± 13

 12 month systolic BP (preHD)

mmHg

136 ± 22

138 ± 20

 12 month diastolic BP (preHD)

mmHg

68 ± 15

69 ± 11

 BP-drugs excl. Placebo/ARB

n

2.6 ± 1.0

2.5 ± 0.9

 BP-drugs excl. Placebo/ARB

DDD

1.8 ± 1.3

1.8 ± 1.2

Dialysis parameters

 Time on dialysis

days

141 (53–431)

148 (54–400)

 AV-fistula/central catheter

n (%)

35 (88)/5 (12)

32 (78)/9 (22)

 Urine output

L/24 h

1.3 ± 0.7

1.4 ± 0.8

 Glomerular filtration rate

mL/min/1.73 m2

4.8 ± 2.3

5.7 ± 3.3

 Frequency

times/week

3 (2–3)

3 (2–4)

 HD-time

hours/week

10 ± 2

11 ± 3

 Ultrafiltration

L

1.2 (0–4.3)

0.5 (0–3.8)

 Urea reduction ratio

%

64 ± 8

62 ± 9

 Hematocrit (EVF)

 

0.33 ± 0.05

0.34 ± 0.04

  1. Heart disease included various conditions such as ischemic heart disease, mild heart failure (LV EF > 30%) and valvulopathy. Ischemic heart disease was defined by the presence of known ischemic heart disease, angina, pre-trial myocardial infarction, and pre-trial PCI or CABG treatment. LV Left ventricular; EF Ejection fraction; BP Blood pressure; preHD Pre-hemodialysis; DDD Defined daily doses; EVF Erythrocyte volume fraction