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Table 4 Univariate regression analysis with change in log (TnT) (Δ = 12 months-baseline)

From: High-sensitivity Troponin T in hemodialysis patients: a randomized placebo-controlled sub-study investigating angiotensin-II-blockade, variation over time and associations with clinical outcome

Parameter

n

β (95% CI)

P

r2

Age at baseline

54

0.005(−0.002; 0.013)

0.13

0.04

Heart disease

54

0.22 (0.02; 0.42)

0.03

0.08

Diabetes

54

−0.12(−0.34; 0.09)

0.25

0.03

Charlson comorbidity index

54

−0.01(− 0.07; 0.06)

0.87

0.00

ΔGFR (mL/min/1.73m2)

49

−0.03(− 0.10; 0.04)

0.40

0.01

ΔUrine output (L/24 h)

52

0.04(−0.13; 0.21)

0.63

0.00

ΔUltrafiltration (L)

53

−0.02(− 0.12; 0.08)

0.68

0.00

Baseline Cornell (SV3 + RaVL) (mm)

54

0.012 (0.001; 0.022)

0.03

0.09

ΔCornell (SV3 + RaVL) (mm)

54

−0.01(−0.02; 0.01)

0.38

0.02

Baseline PWV (m/s)

53

0.01(−0.02; 0.04)

0.55

0.01

Baseline PWV-tertiles (m/s)

9.5–12.5

27

0.09(−0.19; 0.37)

0.52

0.02

(PWV < 9.5 m/s = ref.)

> 12.5

26

0.13(−0.13; 0.38)

0.32

 

ΔPWV (m/s)

52

0.01(−0.05; 0.06)

0.74

0.00

ΔLV mass index (g/m2)

53

0.003 (0.001; 0.006)

0.01

0.11

ΔLV EF(%)

53

−0.01(−0.02; 0.00)

0.01

0.12

ΔSV2 (mL)

41

−0.01(− 0.01; 0.00)

0.04

0.11

Δlog (NT-proBNP) (log (nmol/L))

54

0.18 (0.09; 0.27)

< 0.001

0.25

ΔHematocrit (EVF)

54

−0.93(−2.94; 1.09)

0.36

0.02

  1. Abbreviations: TnT Troponin T; GFR Glomerular filtration rate; PWV Carotid-femoral pulse wave velocity; LV Left ventricular; EF: Ejection fraction; SV2 Late intradialytic stroke volume 30 min before end of HD; NT-proBNP N-terminal pro b-type natriuretic peptide; EVF Erythrocyte volume fraction