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Table 2 Comparison of baseline characteristics between patients with or without stage II-III AKI

From: Risk factors for severe acute kidney injury among patients with rhabdomyolysis

Variables

Acute kidney injury stage II-III

p

No, n = 165

Yes, n = 164

Age, mean ± SD, days

43.5 ± 16.0

47.8 ± 15.6

0.014

Age group, n (%)

0.024

 Age ≤ 40

69 (41.8)

51 (31.1)

 

 40 < Age < 60

74 (44.8)

74 (45.1)

 

 Age ≥ 60

22 (13.3)

39 (23.8)

 

 Male gender, n (%)

129 (78.2)

117 (71.3)

0.153

 Smoking, n (%)

60 (36.4)

59 (36.0)

0.942

 Chronic alcoholism, n (%)

27 (16.4)

54 (32.9)

0.000

Comorbidity, n (%)

 Hypertension

15 (9.1)

36 (22.0)

0.001

 Diabetes

7 (4.2)

20 (12.2)

0.009

 Hyperlipidemia

12 (7.3)

17 (10.4)

0.322

 Sepsis

83 (50.3)

112 (68.3)

0.001

Laboratory data, mean ± SD

 Hemoglobin (g/L)

105.5 ± 34.3

101.4 ± 39.7

0.314

 Platelets (109/L)

147.4 ± 87.2

138.7 ± 84.8

0.358

 WBC (109/L)

13.5 ± 7.4

17.3 ± 11.1

0.000

 Total bilirubin (μmol/L)

27.8 ± 52.8

51.8 ± 84.4

0.002

 Direct bilirubin (μmol/L)

14.7 ± 36.7

27.7 ± 47.4

0.006

 ALT (U/L)

215.1 ± 336.2

453.6 ± 952.2

0.003

 AST (U/L)

399.0 ± 565.5

1158.9 ± 2224.8

0.000

 Albumin (g/L)

28.6 ± 9.2

29.6 ± 7.5

0.267

 Baseline BUN (mmol/L)

6.9 ± 3.1

12.2 ± 7.7

0.000

 Scr (μmol/L)

78.6 ± 24.7

185.5 ± 138.3

0.000

 Cystatin C (μmol/L)

0.9 ± 0.4

2.2 ± 1.2

0.000

 Uric acid (μmol/L)

252.2 ± 142.9

297.3 ± 148.0

0.005

 Triglycerides (mmol/L)

1.5 ± 2.3

2.2 ± 2.6

0.016

 Cholesterol (mmol/L)

3.1 ± 1.7

2.9 ± 1.8

0.487

 HDLC (mmol/L)

0.9 ± 0.5

0.7 ± 0.4

0.000

 LDLC (mmol/L)

1.6 ± 1.1

1.4 ± 1.1

0.098

 Potassium (mmol/L)

3.9 ± 0.6

4.3 ± 0.9

0.000

 Calcium (mmol/L)

2.0 ± 0.3

1.9 ± 0.3

0.022

 Phosphate (mmol/L)

0.9 ± 0.4

1.6 ± 0.8

0.000

 PT (s)

15.2 ± 4.2

16.1 ± 9.7

0.255

CK group, n (%)

0.000

 1000 < CK ≤5000 (U/L)

109 (66.1)

40 (24.4)

 

 5000 < CK ≤10,000 (U/L)

26 (15.8)

28 (17.1)

 

 CK>10,000 (U/L)

30 (18.2)

96 (58.5)

 

Outcome

 Length of stay, mean ± SD, days

29.4 ± 27.5

26.6 ± 22.1

0.304

 Mortality, n (%)

23 (13.9)

42 (25.6)

0.008

  1. AKI Acute kidney injury, WBC White blood cell, ALT Alanine aminotransferase, AST Aspartate transaminase, BUN Blood urea nitrogen, Scr Serum creatinine, HDLC High density lipoprotein, LDLC Low density lipoprotein, PT Prothrombin time, CK Creatine kinase