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Table 2 Comparison of baseline characteristics between patients with or without stage II-III AKI

From: Risk factors for severe acute kidney injury among patients with rhabdomyolysis

Variables Acute kidney injury stage II-III p
No, n = 165 Yes, n = 164
Age, mean ± SD, days 43.5 ± 16.0 47.8 ± 15.6 0.014
Age group, n (%) 0.024
 Age ≤ 40 69 (41.8) 51 (31.1)  
 40 < Age < 60 74 (44.8) 74 (45.1)  
 Age ≥ 60 22 (13.3) 39 (23.8)  
 Male gender, n (%) 129 (78.2) 117 (71.3) 0.153
 Smoking, n (%) 60 (36.4) 59 (36.0) 0.942
 Chronic alcoholism, n (%) 27 (16.4) 54 (32.9) 0.000
Comorbidity, n (%)
 Hypertension 15 (9.1) 36 (22.0) 0.001
 Diabetes 7 (4.2) 20 (12.2) 0.009
 Hyperlipidemia 12 (7.3) 17 (10.4) 0.322
 Sepsis 83 (50.3) 112 (68.3) 0.001
Laboratory data, mean ± SD
 Hemoglobin (g/L) 105.5 ± 34.3 101.4 ± 39.7 0.314
 Platelets (109/L) 147.4 ± 87.2 138.7 ± 84.8 0.358
 WBC (109/L) 13.5 ± 7.4 17.3 ± 11.1 0.000
 Total bilirubin (μmol/L) 27.8 ± 52.8 51.8 ± 84.4 0.002
 Direct bilirubin (μmol/L) 14.7 ± 36.7 27.7 ± 47.4 0.006
 ALT (U/L) 215.1 ± 336.2 453.6 ± 952.2 0.003
 AST (U/L) 399.0 ± 565.5 1158.9 ± 2224.8 0.000
 Albumin (g/L) 28.6 ± 9.2 29.6 ± 7.5 0.267
 Baseline BUN (mmol/L) 6.9 ± 3.1 12.2 ± 7.7 0.000
 Scr (μmol/L) 78.6 ± 24.7 185.5 ± 138.3 0.000
 Cystatin C (μmol/L) 0.9 ± 0.4 2.2 ± 1.2 0.000
 Uric acid (μmol/L) 252.2 ± 142.9 297.3 ± 148.0 0.005
 Triglycerides (mmol/L) 1.5 ± 2.3 2.2 ± 2.6 0.016
 Cholesterol (mmol/L) 3.1 ± 1.7 2.9 ± 1.8 0.487
 HDLC (mmol/L) 0.9 ± 0.5 0.7 ± 0.4 0.000
 LDLC (mmol/L) 1.6 ± 1.1 1.4 ± 1.1 0.098
 Potassium (mmol/L) 3.9 ± 0.6 4.3 ± 0.9 0.000
 Calcium (mmol/L) 2.0 ± 0.3 1.9 ± 0.3 0.022
 Phosphate (mmol/L) 0.9 ± 0.4 1.6 ± 0.8 0.000
 PT (s) 15.2 ± 4.2 16.1 ± 9.7 0.255
CK group, n (%) 0.000
 1000 < CK ≤5000 (U/L) 109 (66.1) 40 (24.4)  
 5000 < CK ≤10,000 (U/L) 26 (15.8) 28 (17.1)  
 CK>10,000 (U/L) 30 (18.2) 96 (58.5)  
Outcome
 Length of stay, mean ± SD, days 29.4 ± 27.5 26.6 ± 22.1 0.304
 Mortality, n (%) 23 (13.9) 42 (25.6) 0.008
  1. AKI Acute kidney injury, WBC White blood cell, ALT Alanine aminotransferase, AST Aspartate transaminase, BUN Blood urea nitrogen, Scr Serum creatinine, HDLC High density lipoprotein, LDLC Low density lipoprotein, PT Prothrombin time, CK Creatine kinase