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Table 1 Baseline characteristics of study population

From: Age differences in the relationships between risk factors and loss of kidney function: a general population cohort study

    Age (years)     
Variable 40–49
(n = 1775)
50–59
(n = 4386)
60–69
(n = 19,015)
70–79
(n = 18,635)
80 –
(n = 8127)
Overall
(n = 51,938)
p trend
Age (years) 45 ± 3 57 ± 3 65 ± 3 75 ± 3 85 ± 4 70 ± 10 < 0.01
Sex (men) 34% 32% 39% 39% 33% 37% 0.71
eGFR (mL/min/1.73 m2) 86 ± 15 79 ± 14 75 ± 14 69 ± 15 61 ± 17 72 ± 16 < 0.01
eGFR < 60 mL/min/1.73 m2 2% 6% 12% 25% 49% 22% < 0.01
eGFR < 60 mL/min/1.73 m2 and/or proteinuria (≥1+) 7% 11% 17% 29% 53% 26% < 0.01
Systolic blood pressure (mmHg) 118 ± 17 127 ± 18 132 ± 18 136 ± 17 139 ± 18 134 ± 18 < 0.01
Diastolic blood pressure (mmHg) 73 ± 12 78 ± 12 79 ± 11 77 ± 10 75 ± 11 77 ± 11 < 0.01
Hemoglobin (g/dL) 13.5 ± 1.7 13.7 ± 1.4 13.7 ± 1.3 13.2 ± 1.4 12.4 ± 1.4 13.3 ± 1.4 < 0.01
Body mass index (kg/m2) 22.3 ± 3.7 22.7 ± 3.4 22.9 ± 3.1 23.2 ± 3.2 22.5 ± 3.4 22.9 ± 3.3 0.01
Total cholesterol (mg/dL) 201 ± 34 214 ± 36 209 ± 34 201 ± 33 195 ± 33 204 ± 34 < 0.01
Proteinuria (≥1+) 5% 5% 6% 7% 11% 7% < 0.01
Diabetes mellitus 2% 7% 10% 13% 12% 11% < 0.01
Current smoker 26% 19% 14% 10% 5% 12% < 0.01
Treatment of hypertension (%) 7% 22% 36% 51% 60% 43% < 0.01
History of coronary artery disease (%) 2% 4% 9% 16% 26% 13% < 0.01
History of stroke (%) 1% 3% 5% 9% 13% 7% < 0.01
Follow-up period (years) 2.8 (1.1, 4.0) 3.2 (1.8, 4.9) 4.0 (2.1, 4.9) 4.2 (2.8, 5.0) 3.3 (2.0, 4.9) 4.0 (2.1, 4.9) < 0.01
Number of creatinine measurements (n) 3 (2, 4) 3 (2, 5) 4 (3, 6) 5 (3, 6) 4 (2, 5) 4 (3, 6) < 0.01
  1. Continuous variables are expressed as mean ± standard deviation, or median (25th and 75th percentiles). Categorical variables are expressed as numbers (percentage)
  2. Abbreviation: eGFR estimated glomerular filtration rate