Skip to main content

Table 1 Tailored immunosuppressive regimens in the Zurich renal transplant program before 2006 and from 2008 to 2011

From: Tailored immunosuppression after kidney transplantation - a single center real-life experience

Regimen

Patient group

Transplantation until 2006

Transplantation from 2008

1

first transplantation without anti-HLA immunization

cyclosporine, MMF, prednisone

cyclosporine, MMF, prednisone

2a

retransplantation and/or anti-HLA immunization, but without DSA

basiliximab, tacrolimus, MMF, prednisone

basiliximab, tacrolimus, MMF, prednisone

2b

recipient with DSA and negative CDC cross-match

basiliximab, tacrolimus, MMF, prednisone

thymoglobulin, tacrolimus, MMF, prednisone

3

donor risk (age above 75, cold ischemia time > 24 h, DCD)

thymoglobulin, tacrolimus delayed (day 5), MMF, prednisone

thymoglobulin, tacrolimus delayed (day 5), MMF, prednisone

4

ABO blood group incompatibility

(not performed)

rituximab + IADS, tacrolimus, MMF, prednisone

  1. CDC Complement-dependent cytotoxicity, DCD Donor after circulatory death, DSA Donor-specific antibody, IADS Immunoadsorption with Glycosorb column, MMF Mycophenolate-mofetil