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Table 1 Characteristics of study participants

From: Elevated alanine aminotransferase and low aspartate aminotransferase/alanine aminotransferase ratio are associated with chronic kidney disease among middle-aged women: a cross-sectional study

 

CKD

(n = 2677)

Non-CKD

(n = 26,456)

P valuea

Age (years)

53.4 (6.6)

50.4 (6.9)

< 0.001

Height (cm)

161.6 (8.3)

157.3 (5.9)

< 0.001

Weight (kg)

61.4 (12.4)

54.9 (9.7)

< 0.001

Body mass index (kg/m2)

23.4 (4.0)

22.1 (3.7)

< 0.001

Obesity

784 (29.3)

4885 (18.5)

< 0.001

Smoking status

 Current

592 (22.1)

4810 (18.2)

< 0.001

 Former

324 (12.1)

1776 (6.7)

 None

1761 (65.8)

19,870 (75.1)

Alcohol intake

 Everyday

601 (22.5)

4164 (15.7)

< 0.001

 Sometimes

778 (29.1)

7932 (30.0)

 None

1298 (48.5)

14,360 (54.3)

Hypertension

984 (36.8)

7649 (28.9)

< 0.001

Dyslipidemia

1357 (50.7)

10,803 (40.8)

< 0.001

Diabetes

193 (7.2)

888 (3.4)

< 0.001

Creatinine (mg/dl)

0.82 (0.80, 0.90)

0.60 (0.56, 0.69)

< 0.001

eGFR (ml/min/1.73 m2)

56.5 (11.4)

81.4 (13.0)

< 0.001

Proteinuria stage

 A1

2302 (86.0)

26,456 (100.0)

< 0.001

 A2

334 (12.5)

0 (0.0)

 A3

41 (1.5)

0 (0.0)

ALT (U/L)

18 (14, 25)

15 (12, 20)

< 0.001

AST/ALT ratio

1.21 (0.39)

1.30 (0.40)

< 0.001

GGT (U/L)

23 (16, 39)

18 (14, 27)

< 0.001

  1. CKD Chronic kidney disease, eGFR Estimated glomerular filtration rate
  2. ALT Alanine aminotransferase, AST Aspartate aminotransferase, GGT Gamma-glutamyltransferase
  3. Values were mean (standard deviation), median (25th percentile, 75th percentile) or n (%)
  4. aUnpaired t -test, wilcoxon’s rank-sum test or chi-squared test