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Table 3 Association of combination of elevated ALT (ALT > 40 U/L) and elevated GGT (GGT > 50 U/L) with CKD

From: Elevated alanine aminotransferase and low aspartate aminotransferase/alanine aminotransferase ratio are associated with chronic kidney disease among middle-aged women: a cross-sectional study

 

Total

N

CKD

n (%)

Crude

Adjusted

OR (95% CI)

OR (95% CI)

ALT > 40 U/L and GGT > 50 U/L

677

126 (18.6)

2.56 (2.10–3.12)

1.70 (1.38–2.10)

ALT > 40 U/L and GGT ≤ 50 U/L

630

105 (16.7)

2.24 (1.81–2.77)

1.57 (1.25–1.96)

ALT ≤ 40 U/L and GGT > 50 U/L

1860

317 (17.0)

2.30 (2.02–2.62)

1.61 (1.41–1.85)

ALT ≤ 40 U/L and GGT ≤ 50 U/L

25,966

2129 (8.2)

1.00

1.00

  1. ALT Alanine aminotransferase, GGT Gamma-glutamyltransferase, CKD Chronic kidney disease
  2. OR Odds ratio, CI Confidence interval
  3. Adjusted for age, smoking status (none, former or current), alcohol intake (none, sometimes or everyday), obesity, hypertension, dyslipidemia, and diabetes