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Table 2 Counts, treatment times and therapeutic anticoagulation of CVVHD and SLEDD in COVID-19

From: Comparison of different anticoagulation strategies for renal replacement therapy in critically ill patients with COVID-19: a cohort study

 

CVVHD

SLEDD

UFH

Citrate

UFH

Argatroban

LMWH

No. of RRT treatments

13

92

22

27

76

No. of patients

7

18

9

3

7

Total RRT duration, h

274.7

4192.6

179.1

215.6

896.4

Mean duration per RRT, h (SD)

21.1 (20.2)

45.6 (25.6)

8.1 (6.2)

8.0 (4.7)

11.8 (4.7)

Early RRT termination, %

92

55

64

67

30

Therapeutic range, %

81

98

100

96

78

  1. Data reported as counts, mean values (standard deviation) and percentages. For the calculation of the percentage of early hemodialysis termination a minimum operating time per CVVHD treatment of at least 48 h was chosen. Percentages depict portion of treatments running less than 48 h. For the calculation of the percentage of early hemodialysis termination a minimum operating time per SLEDD treatment of at least 10 h was chosen. Percentages depict portion of treatments running less than 10 h. Percentage of aPTT-, post filter calcium, or anti-factor-Xa levels in therapeutic range (UFH: aPTT ≥45 s / 1.5 times baseline; citrate: ionized Ca2+ post filter < 0.35 mmol/L Argatroban: aPTT ≥45 s / 1.5 times baseline; LMWH ≥0.5 IU/mL)