Variable | Total n | n | % |
---|---|---|---|
Male sex | 5121 | 3107 | 60.7 |
Ethnic group | |||
 White | 4918 | 3955 | 80.4 |
 Asian | 579 | 11.8 | |
 Black | 215 | 4.4 | |
 Mixed/other | 169 | 3.4 | |
Primary kidney disease groupa | |||
 Glomerular disease | 5065 | 1467 | 29.0 |
 Systemic diseases affecting the kidney | 304 | 6.0 | |
 Familial/hereditary nephropathies | 593 | 11.7 | |
 Tubulointerstitial disease | 1808 | 35.7 | |
 Miscellaneous kidney disorders | 893 | 17.6 | |
Late presentationb | 3366 | 867 | 25.8 |
Age when first seen (years) (median, IQR) | 3389 | 13.1 | 2.7, 20.0 |
Age at KRT start (years) (median, IQR) | 5085 | 19.1 | 12.9, 24.1 |
Years to KRT start from first nephrology review (median, IQR) | 3370 | 2.0 | 0.2. 5.4 |
Tertiles of year started KRT (median, IQR) | 5085 | 2006 | 2001, 2009 |
 1983–2003 | 5085 | 1936 | 38.1 |
 2004–2008 | 1607 | 31.6 | |
 2009–2014 | 1542 | 30.3 | |
Start modality | |||
 Haemodialysis | 5102 | 2011 | 39.4 |
 Peritoneal dialysis | 1839 | 36.0 | |
 Transplant | 1252 | 24.5 | |
 Age at transfer (years) (median, IQR) | 1455 | 18 | 17.4, 18.5 |
Died | 5121 | 260 | 5.1 |
 Age at death (years) (median, IQR) | 260 | 27.6 | 20.3, 32.3 |
Transplanted during study period | |||
 Graft 1 | 4750 | 4377 | 85.5 |
 Graft 2 |  | 371 | 7.2 |
 Graft 3 |  | 2 | 0.04 |
 Re-transplanted during study period | |||
 Graft 2 | 371 | 369 | 7.2 |
 Graft 3 |  | 2 | 0.04 |
Time from listing to transplant (years) (median, IQR) | 4416 | 0.8 | 0.3, 1.8 |
Year of transplant | |||
 1998–2003 | 5121 | 1291 | 25.2 |
 2004–2009 |  | 1930 | 37.7 |
 2010–2014 |  | 1900 | 37.1 |
Donor type | |||
 Live donation | 5121 | 2462 | 48.1 |
 Donation after brainstem death |  | 2356 | 46.0 |
 Donation after circulatory death |  | 303 | 5.9 |
Donor age (years) (median, IQR) | 5115 | 41 | 27, 49 |
Cold ischaemic time (hours) (median, IQR) | 4651 | 9.3 | 2.8, 16.3 |
Calculated reaction frequency (%) (median, IQR)c | 5118 | 0 | 0, 12 |
HLA mismatch groupd | |||
 0 mismatches | 5120 | 544 | 10.6 |
 [0 HLA-DR and 0/1 HLA-B] mismatches | 2016 | 39.4 | |
 [0 HLA-DR and 2 HLA-B] or [1 HLA-DR and 0/1 HLA-B] mismatches | 2272 | 44.4 | |
 [1 HLA-DR and 2 HLA-B] or [2 HLA-DR] mismatches | 288 | 5.6 | |
First eGFR (mL/min/1.73m2) (mean, SD)e | 4882 | 62 | 23 |
Rate of eGFR change (mL/min/1.73m2/year) (mean, SD) | 4487 | −3.14 | 7.69 |
Graft failure | 5111 | 1376 | 26.9 |
 Follow up time (years) (median, IQR) | 5111 | 7.0 | 4.0, 10.9 |
 Time to event (years) (median, IQR) | 1376 | 4.2 | 1.5, 7.6 |
Patient death | 4750 | 238 | 5.0 |
 Follow up time (years) (median, IQR) | 4750 | 8.8 | 5.1, 13.0 |
 Time to event (years) (median, IQR) | 238 | 6.6 | 3.0, 10.6 |
Age at event (mean, SD) | 5111 | 27.5 | 8.7 |