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Table 3 Baseline clinical and laboratorial characteristics for twice weekly patients

From: Safely reducing haemodialysis frequency during the COVID-19 pandemic

 

Completed full trial (n = 113)

Failed twice weekly dialysis (n = 28)

P value

Age (years)

63.1 ± 14.2

65.1 ± 14.7

0.5257

Sex– Male (%)

76 (67.3)

12 (52.2)

0.1686

Ethnicity - White British (%)

78 (69.0)

17 (73.9)

0.6420

Pre HD weight (Kg)

73.5 [62.0–83.2]

76.4 [71.6–86.6]

0.1545

BMI

25.8 [22.7–28.8]

28.2 [24.5–32.9]

0.0395

Last URR (%)a

70.6 [66.2–76.7]

72.5 [69.3–74.3]

0.8383

Corrected Calcium (mmol/L)

2.35 ± 0.18

2.36 ± 0.18

0.7784

Phosphate (mmol/L)

1.55 ± 0.44

1.68 ± 0.56

0.2030

Parathyroid Hormoneb (pmol/L)

28.3 [12.0–59.2]

25.7 [11.6–36.5]

0.3732

Haemoglobin (g/L)

108 ± 15.5

101 ± 19.9

0.0940

Potassium (mmol/L)

4.52 ± 0.77

4.76 ± 0.84

0.1792

Albumin (g/L)

38.3 ± 4.65

35.0 [32.7–40.0]

0.0557

Pre-HD average SBP

148 ± 21.3

149 ± 21.0

0.8362

Pre-HD average DBP

73.9 ± 15.4

74.8 ± 13.1

0.7889

Post-HD average SBPc

138 [125–155]

134 [125–150]

0.5987

Post-HD average DBPd

71.0 [62.5–80.0]

72.0 [64.0–79.0]

0.8243

Average UF (L)

1.30 [1.00–2.00]

2.20 [1.40–2.60]

0.0007

Dialysis Vintage (months)

19.2 (5.3–45.2)

20.7 (8.0–61.4)

0.5270

Primary Renal Disease

 Diabetic Nephropathy (%)

35 (31.0)

9 (39.1)

0.4508

 Hypertensive/Renovascular disease (%)

20 (17.7)

4 (17.4)

0.9727

 Glomerulonephritis (%)

13 (11.5)

5 (21.7)

0.1897

 ADPKD (%)

11 (9.7)

2 (8.7)

0.8821

 Urological (%)

9 (8.0)

1 (4.3)

0.5375

 Pyelonephritis (%)

2 (1.8)

0 (0.0)

0.5183

 ANCA-associated vasculitis (%)

2 (1.8)

0 (0.0)

0.5183

 Other (%)

11 (9.7)

0 (0.0)

0.1207

 Unknown (%)

10 (8.8)

2 (8.7)

0.9877

Comorbidity

 Ischaemic heart disease (%)

21 (18.6)

2 (8.7)

0.2502

 Heart Failure (%)

4 (3.5)

1 (4.3)

0.8523

 CVA (%)

8 (7.1)

6 (26.1)

0.0065

 Diabetes Mellitus (%)

48 (42.5)

10 (43.5)

0.9298

 ACEi (%)

24 (21.2)

5 (21.7)

0.9576

 ARB (%)

18 (15.9)

0 (0.0)

0.0408

  1. Results are expressed as mean ± SD, median [IQR; interquartile range] or n (%).p-value calculated using unpaired T test for parametric data and Mann-Whitney U Test for non-parametric data. Categorical variables were analysed by Chi-square test. Abbreviations: BMI – Body Mass Index, HD – Haemodialysis, SBP – Systolic Blood Pressure, DBP – Diastolic Blood Pressure, URR – Urea Reduction Ratio, ADPKD – Autosomal Dominant Polycystic Kidney Disease, CVA – Cerebrovascular event, ACEi– Angiotensin converting enzyme inhibitor, ARB - Angiotensin receptor blocker. amissing for 13 patients in completed full twice weekly group and 5 patients in failed twice weekly group. bmissing for 1 patient in failed twice weekly group. cmissing for 4 patients in completed full twice weekly group. dmissing for 4 patients in completed full twice weekly group