Parameter, by timepoint | ≤1000 mg (N = 198) | > 1000 mg (N = 58) | Difference (95% CI) | p-value |
---|---|---|---|---|
Hb, g/L | ||||
 After Course 1 (≤1000 mg, n = 194; > 1000 mg, n = 56) | 6.58 (4.94, 8.21) | 10.59 (7.52, 13.66) | 4.02 (0.54, 7.50) | 0.024 |
 Before Course 2 (≤1000 mg, n = 56; > 1000 mg, n = 10) | -0.26 (-3.61, 3.08) | 4.96 (-2.96, 12.88) | 5.22 (-3.40, 13.84) | 0.231 |
 After Course 2 (≤1000 mg, n = 55; > 1000 mg, n = 7) | 8.39 (4.63, 12.16) | 7.79 (-2.85, 18.43) | -0.60 (-11.93, 10.73) | 0.916 |
Ferritin, μg/L | ||||
 After Course 1 (≤1000 mg, n = 157; > 1000 mg, n = 43) | 277.98 (238.50, 317.46) | 306.09 (227.42, 384.75) | 28.10 (-60.32, 116.53) | 0.531 |
 Before Course 2 (≤1000 mg, n = 45; > 1000 mg, n = 7) | 91.50 (55.12, 127.88) | 120.25 (4.72, 235.77) | 28.74 (-93.71, 151.19) | 0.638 |
 After Course 2 (≤1000 mg, n = 42; > 1000 mg, n = 6) | 458.23 (317.77, 598.70) | 424.37 (-177.2, 1026.0) | -33.86 (-652.3, 584.61) | 0.912 |
TSAT, % | ||||
 After Course 1 (≤1000 mg, n = 98; > 1000 mg, n = 31) | 8.13 (5.86, 10.40) | 9.90 (5.36, 14.45) | 1.77 (-3.33, 6.87) | 0.492 |
 Before Course 2 (≤1000 mg, n = 35; > 1000 mg, n = 7) | 0.89 (-0.95, 2.74) | 2.36 (-2.21, 6.94) | 1.47 (-3.56, 6.49) | 0.555 |
 After Course 2 (≤1000 mg, n = 26; > 1000 mg, n = 5) | 14.89 (8.42, 21.35) | 13.17 (-1.60, 27.94) | -1.72 (-18.18, 14.75) | 0.830 |
Platelets, × 109/L | ||||
 After Course 1 (≤1000 mg, n = 127; > 1000 mg, n = 45) | -17.21 (-25.36, -9.06) | -25.75 (-39.47, -12.03) | -8.54 (-24.57, 7.49) | 0.294 |
 Before Course 2 (≤1000 mg, n = 47; > 1000 mg, n = 10) | -0.91 (-17.99, 16.17) | 20.25 (-18.25, 58.75) | 21.16 (-21.07, 63.38) | 0.318 |
 After Course 2 (≤1000 mg, n = 49; > 1000 mg, n = 4) | -14.74 (-33.14, 3.67) | -24.17 (-109.5, 61.17) | -9.44 (-96.73, 77.86) | 0.828 |