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Table 1 Baseline clinical characteristics, measures of liver function, FBC and cardiometabolic markers stratified by eGFR

From: Baseline liver function tests and full blood count indices and their association with progression of chronic kidney disease and renal outcomes in Aboriginal and Torres Strait Islander people: the eGFR follow- up study

Baseline variable

eGFR (CKD EPI) < 60 ml/min per 1.73 m2

(n = 83)

eGFR (CKD EPI) 60–89 ml/min per 1.73 m2

(n = 110)

eGFR (CKD EPI) > 90 ml/min per 1.73 m2

(n = 354)

P Value*

Total

(N = -547)

Age (years)

58.5 (12.6)

51.1 (13.6)

41.6 (13.1)

< 0.001

46.1 (14.6)

Female n (%)

49 (59)

60 (54.5)

239 (67.1)

0.533

348 (63.6)

Diabetes n (%)

54 (65.1)

50 (45.6)

135 (38.1)

0.007

239 (43.7)

ALT (U/L)

23 (17.5–29.5))

27 (19–36)

26 (19–38)

0.005

26 (19–36)

GGT (U/L)

32 (23–77)

33 (22–50)

34 (25–58)

0.391

34 (24–61)

ALP (U/L)

121.5 (96–156.5)

95 (76–112)

93 (77–119)

< 0.001

96 (78–122)

ACR (mg/mmol)

53.7 (12.4–220.9)

1.6 (0.8–13.1)

1.5 (0.7–7.0)

< 0.001

2.1 (0.7–17.7)

CRP (mg/L)

5.0 (3.0–13.0)

5.0 (2.5–9.0)

6.0 (3.0–11.0)

0.646

5.8 (3–11)

Albumin (g/L)

39.4 (4.6)

42.3 (3.98)

42.6 (4.1)

< 0.001

42.1 (4.3)

Bilirubin (μmol/L)

5 (3–8)

7 (5–10)

7 (5–9)

0.002

6.5 (7.9–9.6)

WBC (×109)

8.1 (3.5)

7.78 (3.3)

7.8 (3.2)

0.650

7.9 (3.2)

Hb (g/L)

124.1 (18.8)

135.5 (16.7)

139.3 (16.4)

< 0.001

136.3 (17.6)

RBC (× 1012)

4.1 (1.7)

4.7 (1.0)

4.6 (1.5)

0.060

4.6 (1.4)

SBP (mmHg)

123.0 (17.4)

120.2 (21.0)

116.5 (16.1)

0.002

118.2 (17.5)

DBP (mmHg)

74.5 (9.8)

74.5 (9.8)

74.8 (10.5)

0.712

74.7 (10.2)

WHR (0.1 unit)

1.0 (0.08)

0.9 (0.1)

0.9 (0.1)

< 0.001

0.9 (0.1)

HbA1c (%)

6.5 (5.9–8.4)

6.1 (5.7–7.2)

6.0 (5.6–7.0)

0.012

6.1 (5.6–7.3)

HbA1c (mmol/L)

47.5 (41.0–68.3)

43.2 (38.8–55.2)

42.1 (37.7–53.0)

0.012

43.2 (37.7–56.3)

Cholesterol (mmol/L)

4.5 (1.1)

4.8 (1.1)

4.9 (1.1)

0.012

4.8 (1.1)

Triglycerides (mmol/L)

2.2 (1.6–3.4)

1.8 (1.2–2.4)

1.8 (1.3–2.5)

0.069

1.8 (1.3–2.5)

  1. Data are mean (SD) or median (25th, 75th percentile) unless otherwise specified. CKD-EPI CKD-Epidemiology Collaboration, ALT Alanine Aminotransferase, GGT Gamma-glutamyl transferase, ALP Alkaline phosphatase, ACR Albumin to creatinine ratio, CRP C-reactive protein, FBC Full Blood Count, WBC white blood cell count, Hb haemoglobin, RBC red blood cell count, SBP Systolic blood pressure, DBP diastolic blood pressure, WHR waist-hip ratio, HbA1c glycated haemoglobin, U/L units per litre, g/mol grams per mol, g/L grams per litre, mmHg millimetres of mercury, mmol/L millimoles per litre, ng/L nanograms per litre, pg/L picograms per litres. *p-value of comparisons across eGFR categories and was calculated using ANOVA for continuous variables and logistic regression for categorical variables
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BMC Nephrology

ISSN: 1471-2369

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