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Fig. 1 | BMC Nephrology

Fig. 1

From: Idiopathic multicentric Castleman disease with Sjögren’s syndrome and secondary membranous nephropathy: a case report and review of the literature

Fig. 1

Histopathological findings on renal and inguinal lymph node biopsies. Renal (a-b) and lymph node biopsies (c-f) at the onset of disease. a Diffuse endocapillary and mesangial cell proliferation (PAS staining, × 400). b Lymphocyte and plasma cell infiltration in the tubulointerstitium (HE staining, × 400). c Lymphoid follicles were increased in number, and had hyperplastic germinal centers in the lymph nodes were detected (HE staining, × 40). d Shown are atrophic germinal centers, with small vessels reaching germinal centers, onion-skinning mantle zones (HE staining, × 200). e CD20+cells were mainly observed in follicular regions (× 200). f Plasmacytosis highlighted with CD138 staining in the interfollicular space is shown (× 200)

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BMC Nephrology

ISSN: 1471-2369

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