Variable | All participants | CKD stage 1 | CKD stage 2 | CKD stage 3 | CKD stage 4 | CKD stage 5 ND | p-values |
---|---|---|---|---|---|---|---|
No. of participants (n, %) | 580 | 47 (8.1) | 91 (15.7) | 298 (51.4) | 114 (19.7) | 30 (5.2) | – |
Creatinine clearance (mL/min) | 67 (45–100) | 126 (105–147) | 118 (96–130) | 68 (52–83) | 36 (29–46) | 22 (18–26) | < 0.001 |
Urine albumin/creatinine ratio (10−3) | 105 (19–670) | 48 (12–223) | 54 (9–543) | 73 (13–421) | 212 (35–874) | 1050 (326–2141) | < 0.001 |
24-h urine protein (g/d) | 0.3 (0.1–1.1) | 0.2 (0.1–0.7) | 0.2 (0.1–1.0) | 0.2 (0.1–0.9) | 0.4 (0.2–1.4) | 1.8 (0.6–3.5) | < 0.001 |
P-HDL-C (mmol/l) | 1.5 (0.0) | 1.7 (0.1) | 1.7 (0.1) | 1.5 (0.0) | 1.4 (0.1) | 1.2 (0.1) | < 0.001 |
P-LDL-C (mmol/l) | 3.1 (0.0) | 3.2 (0.1) | 3.4 (0.1) | 3.0 (0.1) | 2.9 (0.1) | 2.8 (0.2) | 0.004 |
P-triglycerides (mmol/l) | 1.5 (1.0–2.2) | 1.0 (0.8–2.0) | 1.2 (0.9–2.0) | 1.6 (1.1–2.2) | 1.6 (1.2–2.2) | 1.8 (1.4–2.6) | 0.008 |
P-glucose (mmol/l) | 5.7 (5.1–6.4) | 5.4 (4.8–6.0) | 5.5 (5.0–6.0) | 5.7 (5.2–6.8) | 5.8 (5.2–6.7) | 5.8 (5.3–6.9) | < 0.001 |
P-Ca2+ (mmol/l) | 1.22 (0.00) | 1.23 (0.01) | 1.23 (0.00) | 1.22 (0.00) | 1.20 (0.01) | 1.18 (0.01) | < 0.001 |
P-phosphate (mmol/l) | 1.08 (0.01) | 0.98 (0.03) | 0.98 (0.02) | 1.02 (0.01) | 1.20 (0.02) | 1.55 (0.05) | < 0.001 |
P-Mg (mmol/l) | 0.84 (0.00) | 0.78 (0.01) | 0.8 (0.01) | 0.83 (0.01) | 0.87 (0.01) | 0.91 (0.03) | < 0.001 |
P-PTH (pmol/l) | 7.2 (4.7–11.5) | 4.4 (3.5–5.4) | 4.8 (4.0–6.4) | 7.2 (5.1–10.0) | 12.7 (8.3–18.9) | 25.0 (14.3–30.7) | < 0.001 |