Table 4 Adjusted associations between cardiovascular risk factors and arterial calcification in the five arterial regions
Variable | Total carotid arteries (n = 526) | Total coronary arteries (n = 535) | Total thoracic aorta (n = 494) | Abdominal aorta (n = 525) | Total iliac arteries (n = 502) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
IRR (95%CI) | P-value | IRR (95%CI) | P-value | IRR (95%CI) | P-value | IRR (95%CI) | P-value | IRR (95%CI) | P-value | |
Age (y) | 1.09 (1.06–1.11) | 0.000 | 1.10 (1.07–1.13) | 0.000 | 1.20 (1.18–1.23) | 0.000 | 1.14 (1.12–1.16) | 0.000 | 1.13 (1.10–1.15) | 0.000 |
Male sex | 0.98 (0.55–1.80) | 0.994 | 2.33 (1.35–4.00) | 0.002 | 0.87 (0.60–1.27) | 0.482 | 1.21 (0.82–1.78) | 0.331 | 2.31 (1.55–3.45) | 0.000 |
Hypertension | 3.17 (1.53–6.55) | 0.002 | 1.92 (0.97–3.80) | 0.061 | 3.11 (1.73–5.56) | 0.000 | 2.67 (1.54–4.62) | 0.000 | 2.09 (1.19–3.69) | 0.011 |
Diabetes | 1.99 (1.01–3.91) | 0.05 | 1.68 (0.88–3.22) | 0.119 | 0.89 (0.52–1.49) | 0.647 | 1.11 (0.66–1.88) | 0.395 | 1.29 (0.75–2.21) | 0.353 |
Cholestesterol- lowering medication | 1.66 (0.98–2.82) | 0.058 | 1.88 (1.11–3.20) | 0.020 | 2.54 (1.67–3.86) | 0.000 | 1.65 (1.09–2.51) | 0.018 | 1.66 (1.09–2.55) | 0.019 |
Per 10 units increase in pack-years of smoking | 1.23 (1.09–1.39) | 0.001 | 1.08 (0.97–1.21) | 0.358 | 1.29 (1.16–1.43) | 0.000 | 1.21 (1.10–1.34) | 0.000 | 1.30 (1.17–1.45) | 0.000 |
Anticoagulants (Warfarin) | 1.36 (0.53–3.48) | 0.517 | 3.36 (1.34–8.44) | 0.010 | 1.70 (0.82–3.55) | 0.156 | 1.65 (0.80–3.42) | 0.117 | 1.76 (0.82–3.76) | 0.146 |
Per 10 units decrease in creatinine clearance (ml/min) | 1.03 (0.96–1.10) | 0.367 | 1.08 (1.02–1.14) | 0.012 | 1.04 (1.01–1.08) | 0.037 | 1.03 (0.98–1.08) | 0.186 | 1.01 (0.95–1.06) | 0.797 |