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Table 4 Univariate and multivariate logistic regression analysis of different BP indexes for TOD

From: Ambulatory blood pressure is better associated with target organ damage than clinic blood pressure in patients with primary glomerular disease

 

Odds ratio (95% CI), P value

Clinic SBP (per 1 SD)

24 h SBP (per 1 SD)

Daytime SBP (per 1 SD)

Nighttime SBP (per 1 SD)

LVH

 Unadjusted

2.130 (1.773, 2.557),< 0.001

2.787 (2.272, 3.420),< 0.001

2.672 (2.184, 3.270),< 0.001

2.720 (2.233, 3.314),< 0.001

 Model 1(M1)

1.321 (1.049, 1.665), 0.018

1.598 (1.230, 2.077),< 0.001

1.529 (1.181, 1.980), 0.001

1.624 (1.267, 2.083),< 0.001

 Model 2 (M1 + Clinic SBP)

–

1.510 (1.128, 2.021), 0.006

1.432 (1.072, 1.912), 0.015

1.545 (1.186, 2.014), 0.001

 Model 3 (M1 + Nighttime SBP)

1.145 (0.891, 1.472), 0.290

–

–

–

eGFR < 60 ml//min per 1.73 m2

 Unadjusted

2.537 (2.189, 2.942),< 0.001

3.003 (2.573, 3.504),< 0.001

2.899 (2.490, 3.376),< 0.001

2.863 (2.455, 3.337),< 0.001

 Model 4(M4)

1.265 (0.991, 1.615), 0.059

1.457 (1.145, 1.854), 0.002

1.415 (1.115, 1.796), 0.004

1.492 (1.181, 1.885), 0.001

 Model 5 (M4 + Clinic SBP)

–

1.416 (1.073, 1.867), 0.014

1.365 (1.036, 1.798), 0.027

1.446 (1.123, 1.863), 0.004

 Model 6 (M4 + Nighttime SBP)

1.089 (0.834, 1.423), 0.529

–

–

–

ACR ≥ 30 mg/g

 Unadjusted

1.684 (1.373, 2.065),< 0.001

1.810 (1.474, 2.221),< 0.001

1.753 (1.433, 2.145),< 0.001

1.981 (1.597, 2.457),< 0.001

 Model 7(M7)

1.409 (1.080, 1.837), 0.011

1.546 (1.194, 2.002), 0.001

1.501 (1.164, 1.935), 0.002

1.730 (1.326, 2.256),< 0.001

 Model 8(M7 + Clinic SBP)

–

1.436 (1.065, 1.935), 0.018

1.384 (1.030, 1.860), 0.031

1.638 (1.231, 2.180), 0.001

 Model 9(M7 + Nighttime SBP)

1.156 (0.867, 1.541), 0.323

–

–

–

cIMT ≥ 0.9 mm or plaque

 Unadjusted

1.623 (1.413, 1.864),< 0.001

1.517 (1.320, 1.742),< 0.001

1.487 (1.295, 1.708),< 0.001

1.566 (1.365, 1.796),< 0.001

 Model 10(M10)

1.088 (0.898, 1.318), 0.389

1.044 (0.856, 1.273), 0.669

1.045 (0.858, 1.273), 0.663

1.070 (0.885, 1.294), 0.482

 Model 11 (M10 + Clinic SBP)

–

1.003 (0.800, 1.256), 0.981

1.003 (0.800, 1.256), 0.981

1.044 (0.851, 1.281), 0.681

 Model12(M10 + NighttimeSBP)

1.071 (0.870, 1.317), 0.519

–

–

–

  1. M1, M4, M7, M10 were short for Model 1, Model 4, Model 7 and Model 10, respectively. Model 1 included adjustment for age, sex, BMI, smoking, alcohol consumption status, hemoglobin. Albumin, eGFR, number of BP medications and type of glomerular disease. Model 4 included adjustment for age, sex, BMI, smoking, alcohol consumption status. Hemoglobin. albumin, ACR, iPTH, uric acid, calcium* phosphate product, number of BP medications and type of glomerular disease. Model 7 included adjustment for age, sex, BMI, smoking, alcohol consumption status, hemoglobin, albumin, uric acid, number of BP medications and type of glomerular disease. Model 10 included adjustment for age, sex, BMI, smoking, alcohol consumption status, eGFR, LDL-C, statin use, number of BP medications and type of glomerular disease. Model 2,5,8,11 included adjustment for the variables in Model 1,4,7,10 respectively and additional adjustment for clinic SBP when examining 24 h/daytime/nighttime SBP as the independent variable. Model 3,6,9,12 included adjustment for the variables in Model 1,4,7,10 respectively and additional adjustment for nighttime SBP when examining clinic SBP as the independent variable. Odds ratios in the table above present 1 SD increase in SBP
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BMC Nephrology

ISSN: 1471-2369

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