Table 1 Baseline characteristics and outcomes of the study population by presence or absence of severe AKI within 7 days
Variable | Severe AKI | Non-Severe AKI | P Value |
|---|---|---|---|
N | 96(16.6) | 481(83.4) | Â |
Age (years) | 73(58–81) | 67(51–77) | 0.004 |
Male | 64(66.7) | 301(62.6) | 0.448 |
BMI (kg/m2) | 26.18(23.03–29.41) | 24.8(22.86–27.68) | 0.037 |
SAPSII | 44(34–52) | 38(27–50) | 0.153 |
Chronic risk factors | |||
 Age > 65 years | 66(68.8) | 256(53.2) | 0.005 |
 BMI > 30 kg/m2 | 21(21.9) | 61(12.7) | 0.039 |
 Hypertension | 48(50) | 212(44.1) | 0.49 |
 DM | 21(21.9) | 66(13.7) | 0.138 |
 CKD | 20(20.8) | 39(8.1) | <0.001 |
 Lung diseases | 8(8.3) | 43(8.9) | 0.848 |
 CVD | 10(10.4) | 58(12.1) | 0.649 |
Acute risk factors | |||
 Sepsis | 20(20.8) | 41(8.5) | <0.001 |
 Surgery | 18(18.8) | 67(13.9) | 0.224 |
 Vasopressor | 46(47.9) | 179(37.2) | 0.05 |
 Mechanical ventilation | 71(74) | 329(68.4) | 0.281 |
 MAP< 70 mmHg | 40(41.7) | 109(22.7) | <0.001 |
Biochemical indicators | |||
 Serum creatinine, admission (mg/dl) | 1.08 (0.75–1.45) | 0.83(0.65–1.08) | <0.001 |
 Serum lactate, admission (mmol/l) | 2.1(1.4–3.8) | 1.6(1.2–2.6) | 0.001 |
 NephroCheck value, admission((ng/ml)2/1000) | 0.66(0.23–2.49) | 0.29(0.08–0.86) | <0.001 |
 PCT, admission (ug/l) | 1.19(0.28–6.81) | 0.26(0.10–1.45) | <0.001 |
 Nephrocheck (+) | 69(71.9) | 233(48.4) | <0.001 |
 PCT (+) | 54(56.3) | 115(23.9) | <0.001 |
Outcomes | |||
 CRRT | 11(11.5) | 6(1.2) | <0.001 |
 Death | 32(33.3) | 63(13.1) | <0.001 |
 LOS(d) | 5(2–8) | 3(2–7) | 0.034 |