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Fig. 1 | BMC Nephrology

Fig. 1

From: Immunohistochemical study for the expression of leukocyte adhesion molecules, and FGF23 and ACE2 in P. gingivalis LPS-induced diabetic nephropathy

Fig. 1

Immunostaining of VCAM-1 in the diabetic mouse kidney with Pg-LPS-induced nephropathy. Hematoxylin-Eosin staining (HE) (left column); immunostaining for VCAM-1 (red) (center column); and merged immunostaining for VCAM-1 and podoplanin (green) (right column), with DAPI staining of nuclei (blue). The glomerular epithelial cells were immunostained by anti-podoplanin to be able to discriminate glomeruli (arrows). Reaction with anti-VCAM-1 were not identified in LPS-ICR (top row) or in STZ-ICR (middle row) while the reaction was identified in renal tubules (arrowheads) and in glomeruli (yellow arrowheads) LPS-STZ (bottom row). Podoplanin-positive macrophages were also identified in STZ-ICR (yellow arrows). Bars: 100 μm

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BMC Nephrology

ISSN: 1471-2369

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