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Fig. 6 | BMC Nephrology

Fig. 6

From: Immunohistochemical study for the expression of leukocyte adhesion molecules, and FGF23 and ACE2 in P. gingivalis LPS-induced diabetic nephropathy

Fig. 6

Quantitative analysis of the immunostaining of renal physiologically active molecules, leukocyte adhesion molecules, and leukocytes. Immunostained areas were measured in microscopic images by ImageJ. Relative expression area was expressed by arbitrary unit: Positive area of ICR (no treatment), STZ-ICR (STZ) and LPS-STZ / the area of LPS-ICR (LPS). The VCAM-1, E-selectin, Mac-1, podoplanin, FGF-23, and ACE2 positive area were significantly larger in LPS-STZ (*) than in ICR, LPS or STZ. The Mac-1 and podoplanin positive area were significantly larger in STZ (**) than in ICR, or LPS. *,**Significantly different by one-way ANOVA

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BMC Nephrology

ISSN: 1471-2369

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