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Table 5 Logistic regression model with group (Case = 1 and Control = 0) as the outcome variable (Odds ratio -OR- and 95% confidence interval- CI). Variables associated with group are investigated by univariate and multivariate models

From: The association of erythropoietin-stimulating agents and increased risk for AV-fistula dysfunction in hemodialysis patients. A retrospective analysis

 

Univariate

Multivariate model

  

Step I a

Final model b

Variable

OR (CI)

p-value

OR (CI)

p-value

OR (CI)

p-value

Iron, mg/W

1.01 (1.00–1.02)

0.002

1.01 (0.99–1.01)

0.209

–

–

ESA, U/Wd

1.11 (1.06–1.17)

< 0.001

1.15 (1.07–1.23)

< 0.001

1.15 (1.07–1.23)

< 0.001

LMWH, U/Wd

1.04 (0.99–1.08)

0.054

1.06 (1.003–1.11)

0.049

1.06 (1.01–1.11)

0.013

Age

0.99 (0.98–1.01)

0.874

–

–

–

–

Female

2.35 (1.47–3.76)

< 0.001

1.91 (0.96–3.80)

0.063

2.26 (1.19–4.27)

0.012

StKt/V

0.40 (0.23–0.61)

< 0.001

0.59 (0.28–1.22)

0.158

–

–

Doxazocin

3.07 (1.58–5.95)

0.001

2.74 (1.04–7.24)

0.042

3.99 (1.57–10.13)

0.004

CRP

0.99 (0.99–1.07)

0.545

–

–

–

–

PTH

0.99 (0.98–0.99)

0.027

0.99 (0.98–1.01)

0.823

–

–

HbA1c c

1.04 (1.02–1.07)

< 0.001

-

 

–

–

  1. aVariables from the univariate analysis with p-value< 0.1 included in step I; bBackward Stepwise model (Wald), cHbA1c included several missing data (around 50%) and is therefore not included in the multivariate model, dOR calculated for a change of a thousand units. HD condition variables were strongly correlated to each other, so we chose to include only one - StKt/V
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BMC Nephrology

ISSN: 1471-2369

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