Granulomatous interstitial nephritis in a patient with SARS-CoV-2 infection

BMC Nephrology

Table 1 Laboratory results

Laboratory Test	Reference range	Admission to hospital (Day 0)^a	Day of transfer to tertiary center (Day 8) ^a	Hemolytic anemia (Day 24)^a	Renal consult (Day 26)^a	Day of Biopsy (Day 32)^a	Day of transfer (Day 48)^a
BLOOD ANALYSIS
Urea, mmol/l	2.76–8.07	-	37.4	CVVHD	CVVHD	CVVHD	29.8
Creatinine, umol/l	59–104	87	498	CVVHD	CVVHD	CVVHD	130
Albumin, g/l	39.7–49.5	-	18.5	19.1	25.8	19.8	22.7
CRP, mg/l	< 5	223	310	339	150	201	27.1
PCT, ng/ml	< 0.5	0.29	2.42	9.13	3.71	5.05	2.56
Ferritin, ug/l	30–400	-	> 11,063	-	2505	4646	3480
D-dimer, mg/l	< 0.5	1.38	3.98	2.55	2.77	2.63	-
IL-6, pg/ml	< 7	-	-	-	-	56.2	-
AST, U/l	< 40	60	252	49	68	73	38
ALT, U/l	< 50	78	146	43	35	47	78
Bilirubin totally, umol/l	3.4–17	-	15.1	29.4	17.3	24	-
Bilirubin indirect, umol/l	< 12.8	-	0.9	3.9	-	-	-
Hemoglobin, g/l	140–180	138	91	69	72	78	71
Schistocytes	-			+		+
Platelet count	139–335 10E3/ul	241	612	598	501	298	513
Haptoglobin, g/l	0.3-2.0	-	-	< 0.1	< 0.1	< 0.1	0.91
LDH, U/l	240–480	770	999	1173	1125	1109	636
Coombs test	Positive/negative	-	-	-	negative	-	-
WBC count	3.5–10 10E3/ml	10	8.6	36.5	25.8	23.8	12.9
Eosinophils	0.08–0.36 10E3/ul	0.01	0.11	0.51	0.12	1.10	0.68
URINE ANALYSIS
Fractional excretion of Urea (%)		-	46.8	-	-	-	-
Urine PCR, mg/mmol	< 20	-	72.6	-	-	-	-
Urine ACR, mg/mmol	< 3	-	5.3	-	-	-	-
Urine, red blood cells, /ul	< 23	10	388	-	13.6	829	3 (03.05.)
Urine, leucocytes, /ul	< 25	15	8	-	5.1	29.1	1 (03.05)

Abbreviations: CRP C-reactive proteine, PCT procalcitonin, IL-6 interleukin 6, AST aspartate amino transferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, WBC white blood cells, PCR protein/creatinine ratio, ACR albumine/creatinine ratio
^a+/- 3 days

ISSN: 1471-2369