Table 5 Univariate and multivariate of primary composite outcome

Normoalbuminuria

Reference

1

Reference

1

Microalbuminuria

1.82 (1.15, 2.89)

0.011

1.4 (0.8, 2.44)

0.235

Macroalbuminuria

4.09 (2.12, 7.88)

< 0.001

3.13 (1.4, 6.96)

0.005

Age (years)

1.04 (1.02, 1.05)

< 0.001

1.02 (1, 1.05)

0.084

Male (%)

1.55 (1.02, 2.36)

0.04

1.26 (0.74, 2.15)

0.397

BMI (kg/m²)

1.02 (0.96, 1.08)

0.498

Systolic BP (mmHg)

1.01 (0.99, 1.02)

0.266

Diastolic BP (mmHg)

1 (0.98, 1.02)

0.867

History of Hypertension

3.26 (2.14, 4.95)

< 0.001

2.6 (1.35, 5)

0.004

History of Type2 DM

3.18 (1.95, 5.19)

< 0.001

1.64 (0.48, 5.66)

0.43

History of Dyslipidemia

1.6 (0.85, 3.02)

0.143

History of smoking (%)

1.33 (0.82, 2.16)

0.249

Serum creatinine (mg/dL)

3.85 (1.53, 9.68)

0.004

eGFR (ml/min/1.73m²)

0.98 (0.97, 0.99)

< 0.001

0.99 (0.98, 1.01)

0.365

Aspirin (use)

6.73 (4.33, 10.49)

< 0.001

5.28 (2.75, 10.14)

< 0.001

ACEI/ARBs (use)

2.86 (1.79, 4.57)

< 0.001

0.64 (0.32, 1.27)

0.204

Insulin (use)

5.67 (2.84, 11.31)

< 0.001

1.19 (0.42, 3.4)

0.738

Metformin (use)

2.41 (1.36, 4.28)

0.003

0.29 (0.09, 0.94)

0.038