Table 3 Characteristics of Patients with positive expression of PLA2R in the glomeruli
PMN (PLA2R positive) (n = 21) | PMN (PLA2R negative) (n = 20) | p-value | |
|---|---|---|---|
Age (years) | 44.71 ± 14.93 | 43.90 ± 20.46 | 0.88 |
Female gender [n (%)] | 11 (52.38) | 14 (70.00) | 0.25 |
Race (Black) [n (%) | 7 (33.33) | 14 (66.67) | 0.82 |
mABP (mmHg) | 93.7 ± 10.8 | 95.48 ± 12.91 | 0.65 |
Presence of oedema (%) | 12 (57.1) | 14 (70.0) | 0.39 |
Hb (g/dl) | 12.1 ± 1.9 | 11.5 ± 2.2 | 0.35 |
Platelet count (x109/L | 363.3 ± 147.5 | 374.7 ± 106.4 | 0.79 |
WBC count (x109/L) | 7.8 ± 2.0 | 9.2 ± 2.7 | 0.06 |
Total cholesterol (mmol/L) | 10.6 ± 4.2 | 8.9 ± 3.5 | 0.25 |
Serum albumin (g/L) | 22.8 ± 6.3 | 20.5 ± 7.9 | 0.34 |
UPCR (g/mmol creatinine) | 0.9 (0.7–1.1) | 0.8 (0.4–1.3) | 0.65 |
Serum creatinine (µmol/L) | 88.0 (64.0–106.0) | 77.5 (61.0–101.0) | 0.50 |
eGFR (mL/min/1.73 m2) | 85.0 (54.0–111.0) | 85.5 (60.0–131.5) | 0.57 |
Tubular atrophy [n (%)] | 5 (23.8) | 2 (10.0) | 0.24 |
Interstitial fibrosis [n (%)] | 5 (23.8) | 7 (35.0) | 0.43 |
IgG positive [n (%)] | 18 (85.7) | 13 (65.0) | 0.12 |
IgA positive [n (%)] | 5 (23.8) | 4 (20.0) | 0.77 |
IgM positive [n (%)] | 11 (52.4) | 5 (25.0) | 0.07 |
C3 positive [n (%)] | 17 (80.9) | 14 (70.0) | 0.41 |