Table 4 Characteristics of Patients with positive expression of PLA2R and LN-V
PMN (PLA2R positive) (n = 21) | LN-V (n = 19) | p | |
|---|---|---|---|
Age (years) | 44.71 | 33.8 ± 13.9 | 0.02 |
Female gender [n (%)] | 11 (52.4) | 17 (89.5) | 0.01 |
Race (Black) [n, %] | 7 (33.3) | 7 (36.8) | 0.82 |
mABP (mmHg) | 93.7 ± 10.8 | 85.7 ± 8.0 | 0.03 |
Presence of oedema [n (%)] | 12 (57.14) | 8 (42.11) | 0.34 |
Hb (g/dL) | 12.1 ± 1.9 | 10.6 ± 2.3 | 0.03 |
Platelet count (x109/L) | 363.3 ± 147.5 | 307.4 ± 149.5 | 0.28 |
WBC count (x109/L) | 7.8 ± 2.0 | 8.5 ± 4.6 | 0.53 |
Total cholesterol (mmol/L) | 9.9 (8.7–11.8) | 4.6 (3.7–5.8) | 0.002 |
Serum albumin (g/L) | 22.8 ± 6.28 | 25.45 ± 7.35 | 0.30 |
UPCR (g/mmol creatinine) | 0.9 (0.7–1.1) | 0.54 (0.3–0.8) | 0.04 |
Serum creatinine (µmol/L) | 88.0 (64.0–106.0) | 72.0 (51.0–123.0) | 0.65 |
eGFR (mL/min/1.73 m2) | 85.0 (54.0–111.0) | 98.0 (49.0–137.0) | 0.74 |
Number of glomeruli per view (n) | 14 (10–20) | 16 (8–20) | 0.97 |
Tubular atrophy [n (%)] | 5 (23.8) | 4 (21.1) | 0.83 |
Interstitial fibrosis [n (%)] | 5 (23.8) | 7 (36.8) | 0.37 |
Immunohistochemistry: | |||
• IgG [n (%)] | 18 (85.7) | 16 (84.2) | 0.89 |
• IgA [n (%)] | 5 (23.8) | 7 (36.8) | 0.37 |
• IgM [n (%)] | 11 (52.4) | 13 (68.4) | 0.30 |
• C3 [n (%)] | 17 (80.9) | 10 (52.6) | 0.06 |