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Table 4 Regression analyses of log-syndecan-1

From: Endothelial glycocalyx damage in kidney disease correlates with uraemic toxins and endothelial dysfunction

Variables

Univariable coefficient β (95% CI)

p-value

R2

Multivariable coefficient β (95% CI)

p-value

Age

0.008 (0.0006 to 0.015)

0.03

0.04

  

Gender

0.40 (0.17 to 0.63)

0.001

0.09

  

eGFRb

-0.004 (-0.007 to -0.0004)

0.03

0.05

  

SBP

0.007 (0.001 to 0.01)

0.01

0.05

  

Diabetes

0.29 (0.04 to 0.54)

0.02

0.04

  

Patient groupa

  

0.41

  

 CKD

0.36 (0.10 to 0.62)

0.01

 

0.36 (0.10 to 0.62)

0.006

 Dialysis

1.10 (0.84 to 1.35)

<0.001

 

1.10 (0.84 to 1.35)

<0.001

 Transplant

0.18 (-0.08 to 0.44)

0.18

 

0.18 (-0.08 to 0.44)

0.181

Log-IS

0.28 (0.20 to 0.36)

<0.001

0.30

  

Log-PCS

0.12 (0.06 to 0.18)

<0.001

0.11

  
  1. Multivariable analysis model R2=0.41
  2. aCompared to healthy controls as the reference group
  3. bExcludes dialysis values