Table 1 General information and results of the biochemical investigations performed in three children
Items | Case 1 | Case2 | Case3 | |
|---|---|---|---|---|
Gender | Male | Male | Male | |
Current age (years) | 3 | 10 | 14 | |
Height (cm) | 101 | 127 | 152 | |
Weight (kg) | 17.7 | 26.4 | 34.7 | |
Blood pressure (mmHg) | 87/46 | 94/54 | 114/88 | |
Chief complaint | proteinuria, polydipsia and polyuria | proteinuria | proteinuria, glycosuria and hypercalciuria | |
Serum investigations | reference range | |||
Albumin (g/L) | 46.5 | 44.1 | 43.2 | 40.0–55.0 |
Prealbumin (mg/L) | 163.3 | 154.2 | 153.3 | 200.0-400.0 |
Sodium (mmol/L) | 135.89 | 133.57 | 140.70 | 137.00-147.00 |
Potassium (mmol/L) | 3.65 | 2.95 | 3.64 | 3.50–5.30 |
Chlorine (mmol/L) | 102.3 | 100.2 | 108.0 | 99.0-110.0 |
Calcium (mmol/L) | 2.56 | 2.45 | 2.31 | 2.11–2.52 |
Phosphate (mmol/L) | 1.40 | 1.41 | 1.29 | 1.45–2.10 |
Cholesterol (mmol/L) | 4.43 | 3.30 | 4.06 | 3.40–5.20 |
Creatinine (µmol/L) | 30.5 | 48.9 | 105.1 | 36.2–52.9 (3y) 44.7–67.7 (10-11y) 52.2–92.8 (14-16y) |
24-h Ccr (ml/min) | 58.09 | 59.95 | 44.26 | 80–120 |
eGFR (mL/min/1.73 m2) | 142.61 | 107.48 | 63.25 | |
Uric acid (µmol/L) | 236 | 267 | 94 | 150–420 |
Urea (mmol/L) | 4.04 | 7.34 | 5.05 | 1.80–7.10 |
Urine investigations | reference range | |||
Protein | 2+ | 2+ | 2+ | negative |
UTP (g/24 h) | 0.50 | 1.28 | 0.92 | 0-0.15 |
Albumin (mg/L) | 165 | 277.00 | 95.20 | 0–19.00 |
ACR (mg/g) | 291.72 | 422.19 | 131.49 | 0–30.00 |
α1-MG (mg/L) | 334.00 | 416.00 | 260.00 | 0–12.00 |
Protein Electrophoresis (%) | negative | |||
LMW protein | 46.5 | 46.9 | 9.5 | |
Albumin | 38.5 | 34.0 | 35.6 | |
HMW protein | 15.0 | 19.1 | 54.9 | |
UCa/Ucr (g/gcr) | 0.19 | 0.34 | 0.50 | 0-0.20 |
Calcium (mmol/24 h) | 0.63 | 7.86 | 8.32 | 2.5–7.50 |
Phosphate (mmol/24 h) | 10.17 | 13.55 | 29.57 | 9.7–42 |