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Table 3 Prediction of renal outcomes among MEST-C scores

From: MEST-C pathological score and long-term outcomes of child and adult patients with Henoch-Schönlein purpura nephritis

Parameters

HR (95% CI) from Model 1

P

HR (95% CI) from Model 2

P

HR (95% CI) from Model 3

P

HR (95% CI) from Model 4

P

Child patients

 M1 (vs. M0)

4.16 (1.394–12.407)

0.011

3.38 (1.101–10.363)

0.033

3.53 (1.118–11.140)

0.032

4.02 (1.217–13.304)

0.023

 E1 (vs. E0)

2.00 (0.734–5.470)

0.175

2.14 (0.720–6.355)

0.171

1.56 (0.486–5.026)

0.453

1.50 (0.464–4.832)

0.499

 S1 (vs. S0)

1.43 (0.553–3.675)

0.463

1.44 (0.554–3.762)

0.452

1.36 (0.508–3.642)

0.540

1.35 (0.494–3.672)

0.560

 T1/T2 (vs. T0)

4.86 (1.406–16.794)

0.012

4.24 (1.124–15.979)

0.033

9.74 (1.920–49.462)

0.006

12.28 (2.728–55.273)

0.001

 C1/C2 (vs. C0)

0.94 (0.396–2.229)

0.887

0.60 (0.232–1.569)

0.300

0.59 (0.231–1.524)

0.279

0.58 (0.216–1.531)

0.268

Adult patients

 M1 (vs. M0)

2.05 (0.756–5.532)

0.159

1.29 (0.420–3.933)

0.659

1.41 (0.411–4.819)

0.586

1.36 (0.410–4.473)

0.618

 E1 (vs. E0)

1.53 (0.569–4.114)

0.399

0.86 (0.233–3.170)

0.820

0.56 (0.139–2.239)

0.410

0.35 (0.075–1.598)

0.174

 S1 (vs. S0)

0.80 (0.299–2.159)

0.664

1.01 (0.354–2.907)

0.979

1.15 (0.371–3.547)

0.812

1.02 (0.357–2.898)

0.974

 T1/T2 (vs. T0)

6.25 (2.265–17.258)

< 0.001

5.32 (1.807–15.660)

0.002

4.29 (1.124–16.333)

0.033

4.02 (1.665–9.684)

0.002

 C1/C2 (vs. C0)

2.43 (0.900–6.553)

0.080

1.95 (0.494–7.717)

0.340

1.57 (0.389–6.334)

0.526

0.85 (0.198–3.639)

0.825

  1. HR Hazard ratio, CI confidence interval
  2. Model 1: Unadjusted
  3. Model 2: Adjusted for other pathological scores
  4. Model 3: Adjusted for model 2 plus age, sex, and estimated glomerular filtration rate
  5. Model 4: Adjusted for model 3 plus proteinuria and hematuria