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Table 4 Predictors of mortality by univariate and multivariable logistic regression analysis

From: Incidence, predictors and prognosis of acute kidney injury in nonagenarians: an in-hospital cohort study

Variables

Mortality

Univariate

Multivariable

Yes (n = 188)

No (n = 248)

OR (CI 95%)

p

OR (CI 95%)

p

Male gender

n/total (%)

56/188 (29.8%)

56/248 (22.6%)

1.45 (0.94–2.24)

0.89

  

Age, years

(mean ± SD)

93.9 ± 3.4

93.3 ± 3.4

1.05 (0.99–1.11)

0.96

1.12 (1.04–1.21)

0.002

Charlson’s

score ≥ 6

n/total (%)

144/188 (76.6%)

111/248 (44.8%)

1.90 (1.30–2.80)

0.01

1.69 (1.01–2.83)

0.049

Length of hospital

stay, days

(mean ± SD)

21.2 ± 20.3

13.1 ± 11.2

1.04 (1.02–1.05)

< 0.001

  

ICU admission

n/total (%)

170/188 (90.4%)

162/248 (65.3%)

5.01 (2.89–8.70)

< 0.001

  

Mechanical

ventilation

n/total (%)

87/188 (46.3%)

9/248 (3.6%)

22.87 (11.08–47.21)

< 0.001

5.29 (2.24–12.46)

< 0.001

Vasopressors

n/total (%)

116/187 (62.0%)

21/248 (8.5%)

17.66 (10.33–30.17)

< 0.001

6.82 (3.55–13.11)

< 0.001

AKI all cases

131/188 (69.7%)

65/248 (26.2%)

6.47 (4.25–9.85)

< 0.001

  

AKI KDIGO 1

49/188 (26.1%)

47/248 (18.9%)

3.35 (2.03–5.51)

< 0.001

2.01 (1.09–3.72)

0.025

AKI KDIGO 2

38/188 (20.2%)

11/248 (4.4%)

11.09 (5.32–23.11)

< 0.001

4.95 (2.05–11.94)

< 0.001

AKI KDIGO 3

44/188 (23.4%)

7/248 (2.8%)

20.18 (8.61–47.27)

< 0.001

6.52 (2.37–17.98)

< 0.001

Community AKI

14/188 (7.4%)

31/248 (12.5%)

1.45 (0.72–2.91)

0.297

  

Hospital AKI

97/188 (51.6%)

28/248 (11.3%)

11.12 (6.65–18.61)

< 0.001

 

Community and Hospital AKI

20/188 (10.6%)

6/248 (2.4%)

10.70 (4.10–27.94)

< 0.001

 

RRT

13/188 (6.9%)

0/248 (0.0%)

(−)

< 0,001

  
  1. Legend: RRT Renal Replacement Therapy, OR Odds ratio, CI Confidence interval, SD Standard deviation, ICU Intensive care unit, AKI Acute kidney injury, KDIGO Kidney Disease Improving Global Outcomes. Note: the following variables entered the multivariable logistic regression model: age, Charlson’s score ≥ 6, length of hospital stay, ICU admission, mechanical ventilation, vasopresssors, AKI stage and RRT. The last column only shows the ones that remained statistically significant at the last step of the multivariable model
  2. Bold entries are variables with p values < 0.10 on univariate analyses were selected for inclusion in stepwise backward multivariable logistic regression models and variables with p values < 0.05 in final analyses were considered statistically significant