Fig. 4

Clinical course of serum creatinine level and urine output and the immunosuppression regimen. After surgery, the serum creatinine level decreased to 0.95 mg/dL, and urine output increased. The immunosuppression regimen was as follows: rituximab, tacrolimus, mycophenolate mofetil, prednisone, and basiliximab. To decrease existing antibody double filtration plasmapheresis and plasma exchange were performed in a presurgical state. At discharge, doses of each immunosuppressive agent were as follows: 7 mg/day tacrolimus, 1000 mg/day mycophenolate mofetil, and 5 mg/day prednisone. On the day of transplantation and postoperative day 4, 20 mg/day basiliximab was administered. POD = postoperative day; TAC = tacrolimus; MMF = mycophenolate mofetil; PSL = prednisone; BXM = basiliximab; RXM = rituximab; DFPP = double filtration plasmapheresis; PE = plasma exchange