Table 2 Patient outcomes
Variable | Overall (n = 1374) | Control group (n = 1047) | Treatment group (n = 327) | p value |
|---|---|---|---|---|
Primary outcome | 342 (24.9) | 245 (23.4) | 97 (29.7) | 0.022 |
 In-hospital mortality | 280 (20.4) | 206 (19.7) | 74 (22.6) | 0.247 |
 RRT dependence | 33 (2.4) | 24 (2.3) | 9 (2.8) | 0.635 |
 No AKI recovery | 183 (13.3) | 129 (12.3) | 54 (16.5) | 0.051 |
AKI max-urine output |  |  |  | < 0.001 |
 No AKI | 254 (18.5) | 199 (19.0) | 55 (16.8) |  |
 Stage 1 | 544 (39.6) | 448 (42.8) | 96 (29.4) |  |
 Stage 2 | 403 (29.3) | 279 (26.6) | 124 (37.9) |  |
 Stage 3 | 173 (12.6) | 121 (11.6) | 52 (15.9) |  |
AKI max-creatinine |  |  |  | < 0.001 |
 No AKI | 577 (42.0) | 523 (50.0) | 54 (16.5) |  |
 Stage 1 | 405 (29.5) | 280 (26.7) | 125 (38.2) |  |
 Stage 2 | 145 (10.6) | 87 (8.3) | 58 (17.7) |  |
 Stage 3 | 247 (18.0) | 157 (15.0) | 90 (27.5) |  |
AKI max |  |  |  | < 0.001 |
 Stage 1 | 635 (46.2) | 538 (51.4) | 97 (29.7) |  |
 Stage 2 | 436 (31.7) | 312 (29.8) | 124 (37.9) |  |
 Stage 3 | 303 (22.1) | 197 (18.8) | 106 (32.4) |  |
RRT during ICU stay | 162 (11.8) | 106 (10.1) | 56 (17.1) | 0.001 |
ICU LOS (days) | 3.4 (1.9–6.6) | 2.8 (1.8–5.6) | 5.5 (3.6–9.6) | < 0.001 |
ICU mortality | 130 (9.5) | 95 (9.1) | 35 (10.7) | 0.379 |
Hospital LOS (days) | 37 (21–66) | 34 (20–62) | 44 (26–76) | < 0.001 |
Dialysis-free survival | 1070 (77.9) | 823 (78.6) | 247 (75.5) | 0.243 |